Plot

Finally ready to work again after giving birth to her baby, Dr. Mike must lead a rescue party when Sully and Cloud Dancing are among the passengers on a train that has been overtaken by robbers and wrecked. Sully had negotiated Cloud Dancing's release from Army detention, and the two were taking the train to Colorado Springs when a gang of thieves derailed the train in an effort to rob it. Meanwhile, Dr. Mike must again face the prejudice against women doctors when she finds that the townspeople have become used to being treated by young Dr. Andrew Cook who filled in for her while she was on maternity leave. For his part, Andrew has become reluctant to return the practice to Dr. Mike and go back to Boston, as originally agreed.

Sully (Joe Lando) and Cloud Dancing's (Larry Sellers) trip back to Colorado Springs takes a terrifying turn when robbers overtake the train. Sully attempts to defend the train, but cannot prevent it from derailing.

Finally ready to work again after giving birth to her baby, Dr. Michaela "Mike" Quinn (Jane Seymour) faces prejudice when she finds the townspeople prefer being treated by young Dr. Andrew Cook (Brandon Douglas), who filled in for her while she was on maternity leave. For his part, Andrew has become reluctant to return the practice to Mike and go back to Boston, as originally agreed. Word of the train wreck reaches town, and Mike must lead a rescue party.