Iced tea was often used to stand in for whiskey on camera. While shooting the scene where Trixie and Sol are arguing and drinking in the Gem, John Hawkes and Paula Malcolmson both had to drink multiple shots of this tea. Normally neither of them drink caffeine, and by the end of the day they were noticeably jittery. Malcolmson had the added burden of smoking numerous cigarettes during the scene, and ended up becoming ill.
A.W. Merrick is apparently a fan of Henry David Thoreau. Visible on the wall of the Deadwood Pioneer office is a framed quote from Thoreau's "Walden." It reads " (The) written word is the choicest of relics. It is something at once more intimate with us and more universal than any other work of art. It is the work of art nearest to life itself. It may be translated into every language, and not only be read but actually breathed from all human lips; - not be represented on canvas or in marble only, but be carved out of the breath of life itself."
Brent Sexton (Harry Manning) worked with Titus Welliver (Silas Adams) on Bosch and Michael Harney (Steve) on Unsolved: The Murders of Tupac and the Notorious B.I.G.