Immediately after takeoff the pilot says that he needs to return and land because the landing gear of the Gulfstream fails to retract (stuck in the down position) after the car explodes beneath. However during the ensuing fight scene between Frank and Gianni each time you see the outside of the Gulfstream (as it spins out of control) the landing gear is clearly up.
When Lola is riding in the car with Frank and the boy, there are some shots of her wearing a seat belt before she actually is shown to put it on right before the building jump.
When Frank drives his Audi through the small white wall at top of the parking lot, he damages the fog lights and lower front bumper. The damage disappears in subsequent shots.
In the doctors office we see Lola's tattoo on her inner thigh and the words "Death by Rabbit" are above and below the rabbit, with no banners. The next time we see the tattoo is when she is getting out of the police car in front of the house and the words are now in banners.
When the A8 is spinning and sliding sideways through the garage, it is knocking down metal support poles. When the vehicle comes to a stop, there is absolutely no damage done to the vehicle from the impacts with the poles.
When waiting in the parking garage Frank's watch beeps. His watch is a Panerai (Panerai Luminor Chrono Daylight, PAM 250) an automatic chronograph with a mechanical drive. It can't beep.
In the Gulfsteam series of aircraft, there is no direct access to the wheel well for the nose gear, thus Frank could never get into the cabin by coming up with the gear.
When the gas is ignited from the cylinder in the doctor's office, the cylinder goes shooting down the hall. You can see that the valve is still intact. In reality, the gas escaping from the cylinder through a valve which is at a ninety degree angle to the cylinder such as the one shown, would force the bottle to spin, not to shoot out and fly in a straight line. Additionally, if the pressure of the gas were enough to move the cylinder, it would do so regardless of the gas being lit on fire. The burning, and subsequently expanding, gas would have no effect on the cylinder once it is outside of the valve as the burning gas does not increase the force on the cylinder.
When the bomb is attached to the bottom of the Audi at the doctor's office, it appears to be magnetic, but the A8 is an all aluminum car with no magnetic material to mount the bomb upon.
In the scene where Frank is fighting Gianni's men in the doctor's office, Lola fires continuously without reloading until she gets outside. The type of machine pistols she uses usually only have 30 rounds per clip or less. However, she fires much more than 30 rounds from each weapon without reloading.
When Frank is walking in the room full of isolation tents for the various test victims of the virus, the tents obviously have positive pressure inside. If one were trying to isolate an airborne contagion inside, positive pressure would not be used; positive pressure is used to keep contagions out, not in.
The pipe used to beat up the thugs in the garage is supposed to be metal, judging by the "clang" noise and sparks when it hits other objects. The pipe flexes badly when it strikes anything else and is obviously made of rubber.
When Frank chases the airplane that is taking off the jet engines clearly have thrust reversers engaged. Those are normally used to slow down the aircraft after landing and would cause the plane to crash if engaged on take-off.
When Frank drives over the wooden bridge at the beach during the Audi chase, the bomb placed on the bottom of the car falls off and is clearly visible on the bridge.
When Frank opens the door to pull Gianni out of the airplane underwater, you can see that the surface of the water outside is about 2 feet above the door. However, once they're out, Frank has to swim up 60-100 feet to reach the same surface.
W12 missing from grill when pulling into house at beginning of movie.
In Dr office after receptionist and Dr shot, no blood splatter anywhere, nor shell casings on floor.
In intro of movie and drone goes over top of Royal Caribbean cruise ship, second pool has no water.
No W12 on grill when going to house for birthday, and many scenes of car chase afterwards.
When the sprinklers came on became of fire in Dr office. Only came on in some rooms, not all.
When Lamborghini is chasing plane, there's a moment when the plane has the air brakes on behind left engine.
When jumping jet ski onto road chasing school bus, it has square bottom.
The Gulfstream III business jet is taking off from an airport on Key Biscayne, Florida. There is no airport on Key Biscayne.
At the 1 hour 6 minute mark, in the garage fight, to avoid the sword strikes, Frank (Jason Statham) uses the bare metal pipes as "monkey bars" of sorts, grabbing them with his bare hands and swinging around them. However, moments later one sword stroke cuts straight through the pipe, and it starts spewing copious steam. Considering that steam in pipes is kept at around 100 to 300°C (up to 572°F), Frank repeatedly grabbing them to swing would have led to instant second-degree burns or worse. Furthermore, there is no way there would be exposed, uninsulated steam pipes in any garage, much less tropical Miami.
When searching a police computer Tarconi claims to be not PC literate due to the fact that in France there is only one PC for every ten policemen, yet he already has a PC in his office, surely for his own private use. He then proceeds to touch-type which would take someone of exceptional IT skills and great levels of dexterity due to the fact that American and French PC keyboards have a different key layout.
All through the movie, Gianni Chellini's name is mispronounced. He is obviously Italian, and so his surname would be pronounced "Kellini". It is instead pronounced as it would be in English; "Chelini".
In the beginning, the girl trying to rob Frank in the garage is not holding her gun properly - her index finger is not on the trigger so she could not fire. Frank should have spotted it easily.