When Donnie Thornberry is being chased, he has Chuckie's sneakers on, but they disappear and reappear in subsequent shots..
Dil disappears during the chase, and is not shown again until the end of the sequence.
When the boat sinks, Charlotte tears the bottom half of her dress to stop the hole. When they get on the island, it is not torn anymore.
Angelica's underwear changes several times, sometimes they are panties and other times more like boxer shorts.
When Susie says "Are you sure [Nigel] can really help us, Tommy?" when they ended up stuck in a cave, her voice is sped up.
Angelica loses her Cynthia doll into the ocean during the middle of the family's cruise during a tropical storm, but it somehow makes it to the uninhabited island, half-buried in the sand the next morning after the weather clears up when they arrive.
This mistake happens in the scene where Nigel and the babies are trapped in the bathysphere underwater, and Nigel is on the radio, chatting with Marianne. He reports: "Well, one little girl is rather pouty, and someone needs a diaper change." However, it has been pointed out in episodes of "The Wild Thornberries" that Nigel is from England. Even though "Rugrats Go Wild" was produced in the United States, Nigel should have used the word "nappy" instead of "diaper". Although, he might have said that because the babies, Angelica and Susie wouldn't know what "nappy" means.