Frank says that he won't do the beer bong because he had a nice Saturday planned out for 'tomorrow', meaning it would be Friday. Then, the high school girl Mitch sleeps with said she has to get to class, which by then it should be Saturday.
The flyers also stated that "Mitch-a-palooza" was on a Thursday night. This means the next day would be Friday.
When Frank is picked up by his wife and friends after streaking, one of the girls in the back seat is shown wearing a hat which subsequently disappears.
Frank's hockey stick changes direction between shots in hands when he breaks the glasses.
Frank has a large Band-Aid on his neck a few scenes before he is shot in the neck with a dart gun. The Band-Aid never shows up again.
When Beanie is in the kitchen describing that they are starting a fraternity, the large black pot on the front left burner keeps moving on and off the burner to the middle of the stove during the scene.
In order for their total score to drop from an 84 average to a 58 average with Blue's 0 scores, there could only have been 2 members (3 if you include Blue). In fact, with 15 members, their score could only drop to a 79.6%.
Set in 2003, Blue's age is revealed to be 89, which makes his date of birth 1914. Blue's picture at his funeral shows him in front of a US flag with 50 stars, which means he would be at least 45 at the time the picture was taken - which clearly he is not. Actor Patrick Cranshaw, who played Blue, was in the US Army Air Force during World War II, so we know it is not him. The photo - whoever is in it - can't be one of Blue.
During the initiation scene, there is absolutely no possibility that a cinder-block would punch the manhole cover in as depicted.
Mitch flies home from San Diego on a British West Indies Airlines (BWIA) L-1011. BWIA doesn't fly from San Diego to New York.
In men's gymnastics the vault is placed vertically, not horizontally as seen when the fraternity is participating in the athletic competition.
When Dean Pritchard reads the scores to the evaluation. A shot reveals the names on the sheet to be the actors' names, not the characters' names.
Near the end, when Frank and Dean Pritchard are tumbling down the classroom stairs, the stuntman for Frank is much smaller than Will Ferrell and also has dark black hair.
The morning after the Mitchapalooza: When Luke Wilson and Elisha Cuthbert wake up in the same bed, and she gets up to get dressed, the sweater she grabs off the nightstand still has a price-tag hanging off it.
Just as Frank falls in the pool after being shot in the neck by a tranquilizer dart, you can see a weight belt around his waist through the robe he is wearing.
When Frank goes streaking outside the fraternity house, he should be completely nude. However, as he's running away we can clearly see that he is wearing a sock to cover up his genitalia.
In the beginning of the movie when Mitch arrives at the San Diego airport, he's seen going down an escalator to catch his flight home. At San Diego's airport you can only get to your gate by going up the escalators.
In the beginning, when Mitch comes home to the "Gang Bang", he greets the dog at the door. The dog is heard panting, but actually isn't.
When Frank is streaking next to his wife's car, you can see the lights and camera attached to the car in the store windows.
When Frank is driving and leaving his messages for his wife, a reflection of the camera and lighting attached to the car can be seen in the windows of the offices in the background.
When Mitch comes home and calls Beanie and Frank into the kitchen about the fraternity Beanie is setting up, a monitor is reflected in the window.
Set in New York State, but in the end credit scene, Frank is shopping at a Jon's supermarket, a California chain.
Mitch-a-palooza is held on a Thursday as stated on fliers. When the college kids goad Frank to have a drink he says he can't because he has plans with his wife tomorrow saying, "We have a nice little Saturday planned." What happened to Friday?
Barry says that the story of Romulus and Remus is Greek. It's really Roman.
Darcie's father says that, "It's hard to believe that in just seven months you'll be graduating from high school." This means that the current month would have to be November or December, yet all the trees and shrubbery in the movie are in full bloom.
During Blue's Funeral the navy emblem on the wreath is designated for Naval Officers. The picture of Blue showed him as an Enlisted meaning he should of had a navy emblem not for officers. The coffin should also have had an American flag draped over it.
Right as the Barry's class begins, Barry tells the women to grab their vegetables. One of the women is using a banana, which is a fruit.