The show would always start with Q.T. and Shamus walking down a dark street. Suddenly a knife was thrown at them and sticks into the light pole next to them. The knife has a note attached which says; "Q.T. Hush Private Eye and Shamus Private Nose".
In color and B&W. Sometimes characters were in B&W while backgrounds were in color. Sometimes all B&W and other times all in color.
This cartoon series was never a "stand-alone" television show. It was always featured in other children programs like Garfield Goose and Friends (1952).