Plot

Scientist Sherman Klump's inventions, his upcoming marriage to his pretty colleague Denise Gaines, and his reputation, are threatened by his evil clone Buddy Love.

Having learned his lesson after the events of The Nutty Professor (1996), meek, gentle Dr Sherman Klump dedicates himself to science. However, when beautiful fellow DNA-researcher Denise Gaines enters the picture, once more, Dr Klump is in love. And, as the love-smitten professor dreams of a brighter future, the lean-and-mean Buddy Love persona emerges, demanding freedom. Now, the nasty alter-ego stands in the way of happiness, and poor Sherman must do everything in his power to rid himself of Buddy once and for all. Can the rowdy Klump family lend a helping hand?—Nick Riganas

Professor Sherman Klump is getting married, and the Klump family could not be more delighted for him. But Buddy Love, his Mr. Hyde alter-ego from the first film, is back and trying to make it on his own. Buddy keeps resurfacing in untimely outbursts, and threatening the portly professor's marriage plans to colleague Denise Gaines. Utilizing Denise's cutting-edge DNA research, Sherman decides to rid himself of his monstrous nemesis--and his disruptive outbursts--once and for all by extracting Buddy's DNA from his system. But Buddy bursts full-bodied into Sherman's world and lays claim to the professor's astounding invention: a revolutionary youth serum. Desperate to keep it from Buddy, Sherman hides the serum in the Klump family home, thinking it will be safe. Buddy correctly divines where Sherman has placed the serum, but to get it, he has to deal with the entire Klump family first.—Anonymous

Sherman Klump is engaged to his pretty girlfriend, fellow professor Denise Gaines. But Buddy Love, his other him from the first movie, tries to stay in his own form for eternity, so he keeps reappearing, which creates chaos for Klump. Klump tries to destroy Buddy Love forever, but while his plan has failed, and he starts to lose his knowledge and memory, he must do something to prevent the loss of the thing that made Denise fall in love with him: his wisdom. With help from his very crude and rude family, the Klumps, he tries to return his memory and to vanish Buddy Love forever.—rsilberman