When Ronna is sitting in Todd's apartment buying drugs, his Santa hat changes from side to side without him moving.
When Tiny is negotiating with the boy in the next hotel room to get through the connecting door to escape Victor Jr/Sr, Tiny's jacket is on/off/on between shots.
When Adam is talking on the phone at Burke's house, the hand he's holding the phone in changes from shot to shot.
When Simon is asking Ronna if she will take his shift, she locks her locker twice before she walks away. And both times puts the lock on backwards.
When the guys from the strip club chase Simon and Marcus to their hotel room, one puts his hand over the eye hole to hide their identities and says "room service." Through the spy hole they see his hand including the fingers. When they then cut to the door you seem him take away his hand which was previously completely covering the spy hole. You wouldn't be able to see any of his hand if he spread his hand completely over the hole.
The phone call between Todd and Simon, in which they talk about the rave and Simon mentions that he knows Claire (who is in the room, as insurance, with Todd), is shown twice. However, they don't coincide with the proper times. When the scene is shown from Todd's perspective, it is night time when he is on the phone with Simon. When the same call is shown from Simon's perspective, it is day time. But Los Angeles and Las Vegas are in the same time zone.
(at around 46 mins) After the fire alarm goes off at the hotel, there is a police officer coming up the elevator to inspect. Law enforcement protocol is to use the stairs, not the elevator in case of fire.
When Ronna, Manny, and Claire play Dead Celebrities in the
back room of the grocery store, Manny says that Omar Sharif is dead. At the time this film was made, he wasn't. However, this could be deliberate to illustrate how little the group really know about deceased celebrities.
When Simon goes to the room with the two girls from the wedding, he claims to discover Tantra mid-intercourse, but this is just a cover-up for his performance failure.
When Vince Sr. and Vince Jr. are chasing Simon, Singh, Tiny, and Marcus in the parkade, Vince Sr. leans on a concrete post that wobbles.
Red painted metal plates can be seen attached to the brick wall where the car crashes in the alley
It is never clear or explained why the character of Simon puts on a fake Irish accent when he meets the two woman at the wedding chapel. He already has a foreign, British accent.
In the parking lot, Zach's line "I didn't pack a bag" does not match his mouth.
At the end of the movie, the camera and director Doug Liman in his baseball cap are reflected in the car window.
When Marcus and Simon are rushing back to get the other two at the hotel, the cameraman (with his white shoes) and his equipment is reflected on the brass wall as the elevator door closes.
When the guys stop on the way to Las Vegas, one of the dressing room trailers is conspicuously parked in the frame.
After Marcus and Simon steal the Ferrari, Simon finds a Beretta 9mm in the glove box and after counting the number of rounds in the magazine he remarks "I hold 10 men's lives in my hand." Marcus replies "It's a 9mm, you don't have the stopping power." All real-world ballistic data shows only a negligible difference between all major cartridges. Shot placement is vastly more important than cartridge used.