- Sir Patrick Stewart plays Captain Jean-Luc Picard across various shows/films
- Famke Janssen (Jean Grey) made her acting debut in Star Trek: The Next Generation: The Perfect Mate (1992). In both these features she played an empathic being who can sense emotions.
- Rebecca Romijn (Mystique) plays Number One in Star Trek: Discovery (2017). Both roles have her as a second-in-command position.
- director Bryan Singer is a Star Trek fan, and eventually got a cameo role in Star Trek: Nemesis (2002).
This adaptation of Cerebro would later appear in the comics as Cerebra, an advanced and upgraded form of Cerebro.
The effect was intentionally added into X2: X-Men United (2003), when Iceman and Rogue share a kiss.