Steven Bochco, who would later became one of the most successful television producers of the 1980s and 1990s, worked on the series very early in his career. He had been hired by Executive Producer Frank Price at the start of the first season to write a few extra minutes worth of scenes in the first six episodes, which were too short. After looking at these episodes, Bochco asked Price if it was really necessary for him to do this for all six because he didn't think the show would last that long. According to Bochco, Price was not happy with the remark, and this was the start of a strained relationship between the two of them that continued when Price was in charge of Universal Television and Bochco was a writer there.
The interior set of Ironside's office was originally constructed for Alfred Hitchcock's 1964 drama Marnie, where it appeared as one of the places of employment whose safe was robbed by kleptomaniac Tippi Hedren.