Goofs

The heart rate shown on the monitors, the heart rate heard by the Proteus crew, and the heart rate specified by the technicians aren't even close to matching.

The number on the nose of the Boeing 707 changes from 6746 to 7744.

After the Proteus has finished Phase 1 shrinking and is placed in a test tube, it submerges and descends deep into the tube. During the descent there are several shots looking up past the commander toward the surface. Many bubbles can be seen rising and striking the surface a short distance above the sub. In each upward shot the distance to the surface never changes, even though the sub is shown to be descending rapidly in other shots.

When Grant's car starts to descend on the elevator, it is parked on concrete. When he leaves the car at CMDF, the material has been changed to dirt.

During the briefing session Dr. Michaels shows the room a diagram of the blood clot on the left side of Benes' brain, and the left carotid artery where the crew will be injected. Once the operation begins though, the needle is injected on Benes right carotid, and all the diagrams thereafter show the Proteus traveling around the right side of his body.

The amount of radioactive material for the sub would not need a lead carrying case. Grant proves this by removing the container from the case with no protection and handing it to Owens who inserts it into the reactor, again bare-handed.

The patient's red blood cells, shown in the various scenes of the miniaturized submarine traveling through blood vessels, are nucleated, which is incorrect. Mammalian, and therefore human, red blood cells have no nuclei; nucleated red blood cells are found in most other animals, however, such as birds, reptiles, amphibians, fish, etc.

Antibodies attack Cora, even though Benes' immune system would never have encountered her before. Antibodies are highly specific to what they bind to, and generally require 5 to 7 days to form against something the immune system has not encountered before.

In addition, the antibodies attack Cora, but not Grant, even though their diving suits are made of the same material. What the antibodies bind to is based on their recognition of the surface of the perceived attacker. In this case, that would be the material of the diving suits, not the shape of her body.

Also, they can sense Cora's location without touching her.

When the outside doctors stopped Benes' heart, the Proteus went through it via the two open valves. This would not be possible though, as once the heart stopped, the arterial pressure beyond the heart would have caused the semi-lunar valve to close.

When they are refilling the air supply, the gauge shows 100 psi when 'full'. That would provide only a few minutes of air. A scuba tank holding 3,000 psi provides about an hour for one diver.

Swim fins were not in use in any of the dive scenes though scuba diving requires them for propulsion. This may have been for the safety of the "divers" who were rigged with wires which have tangled up with the fins.

Actually, swim fins simply "enhance" propulsion. Swimming, even if wearing air tanks, can be accomplished without swim fins.

As the car disappears down the lift, delivering Grant to CMDF, it should vanish as it is hidden by the hole. Instead, the special effects crew elected to shrink the image; at least 20 feet of elevation change is seen at the back wall, but the car is still visible at foreground. In addition, the car's shadow doesn't change as it should if it were actually moving in relation to the light source.

The locking mechanism on the door to the sterilization room serves no purpose; the bars in the star-shaped array get pushed outwards by turning the central wheel and are supposed to interlock with matching holes in the frame to lock the door. There is no frame however, revealing the door as an out-of-place prop.

When the Proteus is buffeted about, the actors sometimes fall in the wrong direction than gravity and inertia would dictate.

(at around 44 mins) A slice of Capt. Bill Owens' right side of head is missing in the vein after the arterial-venous fistula incident, probably due to a mismatched matte.

When the shrunk vessel submerges in the liquid, there are interior shots showing a lot of very small bubbles around the vessel. The depiction of the fluid flow is incorrect. There should be no such small bubbles when such a small object dives as the adhesive forces within the liquid would prevent that. Compared to the shrunk vessel, the bubbles should appear much bigger.

This film/story 'sets aside' numerous facts about the human body, to make it an interesting adventure.

The Proteus is a state-of-the-art submarine, with advanced features and technology, yet In order to submerge, Captain Owens asks Grant to manually open the intake valves on two different sides of the submarine, far away from the pilot and cockpit controls.

There is a shadow visible on the right hand wall as the camera pulls back to see the large control room for the first time (only in widescreen only).

When Grant is being driven up the ramp at CMDF, a shadow of crew member holding a boom is visible at first turn, and another shadow is visible at the top of the ramp just before the camera pulls back.

Wires are visible when the sub is in the lymphatic system just prior to moving to the inner ear. Wires show on the sub, the reticulated fibers, and even on the "invading bodies".

If the crew members can swim from the brain to the eye in around a minute, why didn't they enter from the eye?

When the crew of the Proteus is refilling their oxygen, they are using air from the patient's lung. This air has normally-sized gas atoms, which their miniaturized bodies would not be able to use.

They're cruising around inside the body. Where's all the light coming from?

The entire opening sequence is fairly far-fetched. If they were sneaking Benes into the country, it's unlikely they'd do it with sirens blaring, troop transports, etc. Even if they did, roads would be closed off for blocks, not allowing a stray car to ram the convoy.

While bringing Benes into the country,after his car is rammed, the agents move him from the damaged car to another one. Once in the car enemy shots are heard. Why wouldn't the snipers fire as Benes was being moved, when they had a clear shot at him?

When the nurse is fitting the needle to the hypodermic, she is not wearing surgical gloves, although the machine operators are.

At one point, General Carter stops himself from killing an ant on the table. The CMDF is supposedly a sealed, antiseptic facility. It's doubtful it would have ants.

When divers signal OK, they should use OK with thumb and forefinger. Using thumbs up indicates surface.

Reid and Carter time the restarting of Benes' heart down to the last possible second. Yet when Reid tells the technician "now!" it's actually 12 more seconds before the heart begins again.

Stephen calls Raquel "Clora" instead of "Cora" when alerting her to the laser guns mishap.