Sylvester's owners have gone on vacation and left him alone in a locked house. That's pretty messed up! Sylvester does find a stash of canned tuna in a cupboard but the problem is he can't find a can opener. Turns out a little mouse that's a real jerk has the can opener and taunts Sylvester throughout the cartoon, refusing to let him have it and making him do desperate things to try and open the cans. As others have mentioned, this is one short where you really feel sorry for Sylvester. He's the victim here, both of his owners' neglect and this bastard mouse that torments him for nothing. It's a pretty good cartoon with great animation and music. Some of the gags are very funny although, as I said, you really feel bad for poor Sylvester.