In subsequent scenes Gold Hat's sombrero is missing the bullet hole that Bogart shot into it at the mountain confrontation.
During the fight with McCormick in the cantina, the position of Dobbs' hat on the bar rail changes at least twice.
When the bandits find Dobbs at the waterhole the shadows indicate the time near 12.00. A few minutes later as the bandits chase after the burros the sun is near setting or rising.
As Dobbs tries to catch up to Howard on the street, the bundle under his arm instantly changes from one arm to the other.
When Howard is laid on a hammock, being served by Indian women, he has a little bunch of flowers on his left ear which disappear in subsequent shots.
When Howard is translating for the Mexican, he claims he is warned that there are tigers that can climb trees with birds in their mouths. However, the Mexican says no such thing, only giving a warning of the rough terrain ahead.
In the opening shot of the poster, the word "febrero" ("February") is spelled with a capital F. In Spanish, month names may or may not be capitalized.
Glaringly obvious use of doubles in the bar fight scene to replace Humphrey Bogart, Tim Holt, and Barton MacLane.
When Dobbs douses himself at the watering hole, the water does not get his hair wet, it just pools on his hairpiece.
When Dobbs and his string of burros arrive at the watering hole, he falls face down on the bank and begins to drink. However, if Dobbs is thirsty, then his burros should be thirsty too. Only one of the burros takes a drink, revealing that they're not severely dehydrated.
When Howard and Curtin pursue Dobbs, they pass a "dead" donkey left by Dobbs. The donkey is breathing and the ropes used to tie its legs are visible.
Curtin reads Cody's letter out of sequence. He starts on the front page, then opens to the inside pages. He glances momentarily at page #2 on the left, but immediately starts to read page #3 on the right. He then reads page #2 before turning to the back page.
Although set in the 1920s, many of the cars on the streets of Tampico are of 1930s and 1940s vintage; likewise, women, when prominently seen, are groomed and dressed strictly in the style of the 1940s.
In an early scene when Dobbs is getting a haircut, an automobile flashes past the window of the barbershop. It appears to be a late 1940s sedan.
During the gunfight with the bandidos at the gold mine, Dobbs runs out of bullets while firing his rifle. He is shown reloading it just as the shooting stops. With absolutely no sound coming from the film, Dobbs fires the rifle (trigger pulled and hammer falls) but no noise or muzzle blast is shown. Some may call it a misfire, but there is no sound as the hammer falls and Dobbs would have reacted to a misfire. Just another case of bad editing.
After the first pause in the gun battle Dobbs pulls the trigger of his rifle but it doesn't fire.
During the fight with the bandits, a shadow of a crew member is visible against Curtin's shirt for a few seconds, before he goes to check on the condition of Cody.
Sound truck or panel truck with cables visible when Dobbs is hunting for body to bury.
A crew member's knee and shoulder are seen for several seconds in the scene where they take their first break on the trek.
There are background noises from wildlife in parts of the movie. One of which is the unmistakable call of the Australian kookaburra.
When the main characters start their prospecting in the Sierra Madre, Joshua trees can be seen in the background. There are no Joshua trees in this area as they are native to the United States' southwest, particularly in the Mojave Dessert.
A shadow of the mike boom passes along the top of the barrel as Dobbs and McCormick walk along talking about their pay at the work site.
Howard's translation from Spanish into English is way off and some of his Spanish on the train is just gibberish.
During the reading of Cody's letter, Dobbs prepares a cigarette. He takes the tobacco pouch out of his pocket but doesn't take any tobacco out. He rolls the paper and licks it.
When a restless Dobbs awakens in the middle of the night and goes out to look for Howard who's not in their tent, he encounters Howard returning from checking on the burros. Howard says there's a tiger out, but there are no tigers in Mexico. It could be that he meant to say cougar or bobcat which are native to Mexico.