In the David Stenn biography on Clara Bow, Baby Peggy remarked that during the production of Helen's Babies, Clara was making two other films simultaneously, which caused great confusion for her. Clara would arrive on the set one day wearing a wig from one film, then another wig from another film, which caused much problems on the set of Helen's Babies.
This film was the opening night feature for Cinecon 54 in Los Angeles in honor of cast member Diana Serra Cary's (Baby Peggy) approaching 100th birthday. Cary was unable to attend, but remarked on the film in a videotaped interview that preceded the screening.