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- A college graduate with a once-promising career, Justin has eaten his life away to the point of never leaving the house for anything but food. Now only the help of Dr. Now's weight-loss program can restore his hopes of living a happy, productive life.
- In the 4th year of his weight loss journey, Sean struggles to get past the loss of his mother and live on his own. Dr. Now intervenes to control Sean's eating for a time, but if Sean can't learn to control himself, he will face the direst of consequences.
- Lacey's weight, caused by overeating, keeps her housebound but doesn't deter her love for Ricky. However, Ricky's sister Sharon adds complexity to their relationship.
- Nothing means more to Chris than his relationship with his daughter, Zoey, but now he feels he is failing her as his weight gain begins to limit his mobility. Chris turns to his mother, whom he hasn't seen in seven years, to help get his life on track.
- Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth. Now he weighs 800 pounds, and he's relying on his foster mum to support him as he finds the motivation to change and save his own life.
- With the Perrios struggling with different stages of their weight loss journey, the revelation of a past tragedy explains their resistance to recovery. The siblings must now come together to overcome their fears and forge a path towards a healthy future.
- With the support of his fiance, Kathryn, Robert turns to Dr. Nowzaradan in a final, desperate attempt to save his life. He tries to reverse a lifelong food addiction that has left him bed-bound, saddled with grotesque lymphedema, and nearly 900-lbs.
- Fearing he'll suffer the same fate as 700-pound brother David, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey.
- Twins Kandi & Brandi have a combined weight totaling over 1100lbs. These inseparable twins fear losing each other to obesity, so they make a change together. But a life-threatening event during weight loss surgery recovery may separate them forever.
- Kelly is on the verge of immobility when she decides to make the trip to Houston to visit Dr. Now. Her journey gets off to a painful start when a long travel-day grows longer as Kelly gets stuck in a cab on her way from the clinic to the hospital.
- Cillas' food addiction is getting in the way of his ability to be there for his fiancee, Jessica, and her 3 daughters. If he doesn't lose weight soon, he knows he'll lose either his girls, or his life.
- A couple who love food decide to take on a healthier lifestyle and head to Houston to see Dr. Now. Their relationship is tested as they go on their journey.
- Together weighing more than a ton, siblings Roshanda, Brandie and Clarence set out to lose weight as a family; the all-for-one approach may be hurting more than it helps when each of them shows signs of heading in the wrong direction after surgery.
- Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life. He thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only path forward.
- With her weight spiraling, Stephanie needs her mom's help to care for her three kids. Now, she's at the point where she'll have to lose weight or risk not having the chance to see her kids grow up.
- Battling severe depression in the wake of a suicide attempt, 46-year old Olivia hasn't left her Chicago basement in two years. With one last chance at a new life, Olivia will travel to Houston with the hope of having a life-changing surgery.
- Lee's anger issues continue to jeopardize his relationship with Rena and threatens to derail both of their weight loss journeys, while a major life event sends Sarah into a depression, and she must pull herself out of if she wants to keep losing weight.
- 650-lb Melissa begins her seven-year weight loss journey.
- As an Italian American, Geno was raised with lots of love, family and food. Now, he's still living with his mom and eating himself to death, and it's time to make a change. Geno's cousin, Nico, joins the cause, and they pledge to lose weight together.
- Latonya found the man she wants to marry. The only problem is that, at almost 700 pounds, she can't walk down the aisle. Latonya doesn't want to give up the food that she's used to, but she may do it for love.
- 650-lb Melissa struggles to get to her ideal weight.
- After a difficult childhood with an abusive stepfather and drug-addicted mother, Sarah weighs over 600-lbs and is fighting for her life at only 24 years old.
- J.T. is almost 900lbs with a 100-lb lymphedema mass on his leg and a food addiction that is bound to kill him if he doesn't change. His girlfriend takes him to Houston, but when his behavior drives her away, J.T. is left with only Dr. Now to help.
- Living on a homestead with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.
- For Larry, a second weight loss surgery would mean a second chance at a career as a gospel recording artist. But a beautiful singing voice doesn't pair well with a 600-pound eating habit. If Larry can't make the choice to change, then no one can help him.
- 750-lb Henry begins his weight loss journey in the hopes of transforming himself in time to attend his high school reunion.
- Zsaylnn, once known as the "Fat Girl Rock Star" - married a man who loves large women. Now weighing over 600lbs, she urgently needs to lose weight to be the mother her daughter deserves. Can Zsalynn succeed with a husband who doesn't support her goals?
- At age 23, and over 600-lbs, Amber relies on her family, and boyfriend for even simple needs. Her fear of dying young is so overwhelming that she makes the decision to relocate 2,000 miles in hopes that weight loss surgery will give her life back.
- Brandon is a talented musician with a beautiful voice and a run-away weight problem. He wants more than to lose weight, he wants a career and he wants to take the next step with his girlfriend Taylor whom he risks losing if he can't make a change.
- Steven is healing from weight loss surgery and Justin decides to undergo the same operation. However, Justin reconsiders when his feelings towards his brother.sour.
- Thederick has become housebound from eating, and for 10 years, he's only gone outside to greet the ice cream man. After a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.
- Margaret's life at 700 pounds is in need of a jump start. At age 35, she is a mama's girl. Now, it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.
- John & Lonnie are two brothers from opposite ends of the spectrum; estranged for years, the brothers are brought together by a common need to lose weight while they still can.
- When Travis gets too big to walk down the aisle, he promises his wife a proper wedding, leaving Dr. Now as Travis' only hope to lose weight and get the life he and his wife dreamed of having together.
- Shantel's brother Carlton lives downstairs but she hardly ever sees him because at 600+ lbs each, neither can do the stairs safely. Now to break free from a death spiral of codependent eating they need Dr. Now's help to reforge their sibling relationship.
- Tommy wants to lose weight so he can marry his fiancee and have the life he always dreamed of with her, but to break the cycle of pathological eating that left him nearly bed-bound, he'll have to face a piece of his past he has always kept secret.
- Isaac helped raise his siblings after his mom suffered a debilitating stroke when he was 10. While learning to cook for his family, he began comfort-eating. Now to avoid eating himself to death, Isaac must learn to take care of himself for a change.
- Through tough times, food has always been Tammy's friend. But now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.
- At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister. But if he can't find a way to believe in himself, he'll never be able to stop eating.
- Dolly has gotten too comfortable at 600 pounds. There's physical pain all over, and the skin apron pulling on her abdomen is miserable, but with her mom and others waiting on her hand and foot, she manages to avoid ever taking responsibility for her life.
- Chuck weighs almost 700lbs and it has hindered every aspect of his life. He's had to downsize his business and his wife feels like a single-parent, who is ready to leave him. Can Chuck take control and reclaim the life that's slipping through his fingers?
- James comes from a long line of family obesity and at 706lbs, is determined not to die in the same hospital bed that his father and sister did. James vows to change his lifestyle in order to get gastric bypass, and even has hopes of dating again.
- Tara is a mother of two from Lafayette, LA. Addicted to food, she is too ashamed of her size to be seen with her kids, confining herself indoors. Now seeking gastric bypass, Tara is committed to regaining her confidence and being a proud mother once more.
- Weighing in at over 600-lbs, 37 year old Susan is committed to drastic weight loss. But, when an unforeseen medical disorder strikes her mobility, finding the strength to make it through these obstacles is a matter of life and death.
- Pivotal moments, whether tragic breaking points or ultimate triumphs, decide the success or failure of individuals struggling with extreme obesity. They must face the reality that weight-loss surgery alone is not the answer to reclaiming their lives.
- Christina's weight loss has gone too far, too fast, and now threatens her life. After losing 300lbs, Paula must endure more surgery to deal with a body entirely covered in loose and sagging excess skin.
- Joe has come a long way from being morbidly obese... He's in love and is contemplating proposing to his girlfriend. Charity must find the strength to return to her goals of getting healthy and living a normal life after many post surgery complications.
- A devoted girlfriend and loving aunt, Alicia is all smiles and laughter on the outside, but on the inside she is terrified that her addiction to food will kill her before she can marry her long-time love or watch her nieces grow up.
- After years of a tumultuous relationship with her husband, Tamy's eating addiction has caused her weight to balloon over 500-lbs. She has become a hermit after years of shame, and hopes to restart her life so she can better care for her son Zachary.
- Still 500 pounds and immobile a year after starting her weight loss program, Dr. Now see no other options for treatment for Janine.
- Irene had to move back in with her son because her weight made it unbearable to live on her own. When Dr. Now can't get through to her, the only thing that might help her break the cycle is a once-in-a-lifetime turn of events.
- Bianca is all in for a move to Houston with her boyfriend and two young kids to get Dr. Now's help with a second weight-loss surgery. But just when the coast is clear, her boyfriend's change of mind could undermine her progress.
- At over 700 pounds, Brianne undertakes a weight-loss journey to save her own life and faces an unexpected challenge to her fragile progress when her husband suffers a heart attack on a birthday she will never forget.
- The four best reasons for Coliesa to live are her daughters. But after a heart attack and losing the love of her life in a car crash, Coliesa eats non-stop to escape from reality, and unless she can stop that, the next heart attack will be fatal.
- 2012–6.7 (8)TV EpisodeIf Steve Sr. thought getting weight-loss surgery for his sons would help bring them together, the third year of their weight-loss journey will prove him wrong, as Justin returns to Rhode Island with every intention of never speaking to Steven again.
- Ryan moved to Montana to keep himself from going down a dark path of drug addiction. However, his new path may be no less lethal than the last if he can't find a way to curb his eating habits before they kill him.
- Steven Assanti's dysfunction escalates, pushing his relationship with Dr. Nowzaradan to the brink, and a risky decision is made to save Steven's life, while brother Justin takes the leap to go to Houston to finally accept help.
- Wess gets off to a great start in Dr. Now's program, but when the cravings continue after surgery, Dr. Now sends him to therapy to confront his demons. Now, Wess must ask himself whether he is ready to live his truth as a gay man in small town Texas.
- Shakyia's severe obesity worsened when she became a shut-in. Despite her sister's encouragement, meeting Dr. Now proves difficult, especially without her mother's support.
- At 700lbs, Milla is bedridden and dependent on her husband and five kids. Terrified each day will be her last, they still can't resist her unending requests for junk food. Can Milla stop a lifetime of unhealthy eating to qualify for gastric surgery?
- At 670 pounds Ashley must live in her parents' home with her husband. Desperate to save her life and her marriage, she decides it's time for a drastic change. Can weight loss surgery save her life & give her the chance to have a family of her own?
- Unable to stand for more than a short period of time, Karina's weight has placed a burden on her parents and driven a wedge between she and her sister. Can Karina lose weight and repair the damage to her family?
- A mother of 4, bed-bound for 2 years, Lashanta relies on her kids to keep her cleaned and fed. Her last chance to break the cycle of food addiction that's killing her is to join Dr. Now's program, but it will take a village just to get her out the door.
- For Julian and his wife, Irma, it was love at first sight. But in order to grow old together, Julian will have to overcome the food addiction that made him more than 800 pounds, and Irma will have to hold on no matter how difficult the journey may become.
- Mike was born with a talent for sports--and an omnivorous appetite to match. After his football dreams were dashed by multiple concussions, he packed on over 700 pounds. Now he must find a new purpose in life to avoid succumbing to pain and regret.
- Syreeta thinks that anyone trying to help has an ulterior motive, but now she's gotten so big she desperately needs help. She's learning to let down her guard for her husband, but weight loss surgery will be tough if she can't learn to trust the surgeon.
- At 42 years old, Angel is staring death in the face. She is struggling to make a positive change and be an active part of her partner and son's lives. With so much at stake, can she turn her life around?
- At 650 pounds, Gideon's weight prohibits him from working, making him completely dependent on his exhausted wife. Desperate for change, he uproots his family to restart his life with weight-loss surgery and hopes for a future of happily-ever-after.
- After losing 250lbs, Nikki is on her way to skin surgery that will transform her body. But when a close friend dies from weight loss surgery, Nikki's progress goes off track, derailed by fears of another surgery and if she'll make it out alive.
- James "LB" Bonner spent his early life trying to prove himself to his adoptive family, but after losing a leg and battling obesity, LB must take a new path to save his health and his family relationships.
- After a lifelong struggle with obesity, the three Perrio siblings travel to Houston in a last-chance journey to lose weight. Will they be able to break decades of unhealthy habits without fracturing as a family?
- Despite moving to Houston with the solid support network of her boyfriend Aaron and her cousin Jasmine, Tiffany finds it difficult to break the cycle of depressed eating when her two roommates don't join her diet and leave the house every day for work.
- When Annjeanette was 9, a campaign was established to send her to fat camp. She hated that her weight had become a source of public shame and she has struggled to overcome her food addiction. Now, she must change her habits to save her life.
- Lindsey Witte had it all: a white picket fence, a loving husband, a great job. But now her food addiction is threatening to ruin everything. And as she embarks on a weight loss journey to save her life, is her husband a support or an addict himself?
- A lifetime of abuse and ridicule has left Michael anxious and afraid to leave the house. Now with the help of his devoted wife he must follow Dr. Now's program to keep from eating himself to death.
- For James B, food means family. He grew up eating rich Haitian food and loves it with a passion. Now, James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.
- Patrick's weight has never been a bother, but now he's so big that it's getting in the way of his relationship with his daughter. If he wants to see her graduate high school, he'll have to reverse course.
- Paula has had a tough life, and at over 600lbs, has built a physical wall around herself to push people away. When she suddenly loses someone she loves, Paula can no longer ignore the threat of losing her own life - especially for her children's sake.
- At over 600 pounds, Brittani's eating has enslaved her and left her marriage without intimacy. She must seek help before her body gives out.
- 26-year-old Sean weighs over 700-lbs with a massive growth protruding from his side and skin so stretched it is tearing apart. His mother is forced to change both of their lifestyles before he can be approved for gastric bypass surgery.
- Zsalynn is excited for a fresh start but her 360-body lift at a Beverly Hills clinic proves more challenging than expected. Lonely and depressed since her gastric surgery, Olivia wants skin removal surgery but struggles to lose the weight to qualify.
- After meeting and falling in love at a barriatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their relationship and their lives.
- Jennifer and her daughter Marissa are stuck in a codependent relationship that has put both of their lives in jeopardy, with a combined weight of over 900-lbs. Can Jennifer regain control and save both of their lives before it's too late?
- Jeanne lives in an unhygienic household with her mother and schizophrenic father. At well-over 600 lbs., Jeanne might never get weight-loss surgery as she runs into several obstacles, especially after an unexpected death in her family.
- Bethany has two daughters who live in fear of losing their mom to her food addiction. Once an addiction counselor, Bethany has gotten so big that she can no longer work. Now she risks losing her life, if Dr. Now can't help her curb her own addiction.
- Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body. Now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.
- Ashley's career was derailed after she was let go due to her excessive weight. Will she be able to turn her life around and achieve her goal of owning a childcare facility?
- Christina is a 22-year old married woman from South Haven, Mississippi, who hasn't left her house in two years due to her size. Her doting family has enabled her and she's eaten herself into a state that will soon kill her, if she can't make a change.
- Zsalynn is finally free of Gareth, her ex-husband who wouldn't let her lose weight; Christina faces a difficult challenge when she passes out at home.
- Chuck starts from scratch during his second year of weight-loss, discovering a promising new relationship. Paula juggles many responsibilities head at once, but is it too much to stay on track for her weight-loss goal?
- Joe is only 30, and trapped in an 800-lb body. He lost his job and is mostly housebound. Can Joe find the strength to face his past and save his life?
- Chay is just 23, but to cope with the emotional turmoil of his childhood he has eaten his way to 600-lbs and it's threatening to kill him before turning 30. When Chay loses his emotional support, he must find new strength to take control of his life.
- Weighing over 700 pounds at 26 years old, the clock is ticking on Ashley's life. Ashamed of her body, surgery offers hope, but not without setbacks.
- At 650lbs, Randy's food addiction led to the loss of his marriage and visits with his daughter. To regain control of his life, he endures a rigorous pre-surgery diet, surrounded by fast-food temptations. Will he be approved for a weight-loss operation?
- Most of the extreme weight on Tracey's body resides in her shockingly misshapen legs. They're so massive with severe lymphedema, that gastric surgery is her only chance of survival. Will this mother and grandmother ever gain control of her overeating?
- 2012– 1h 25mTV-146.4 (46)TV EpisodeAfter a year on a weight loss program, Steven remains completely non-compliant, and Justin focuses on a new career instead of his diet... With neither brother close to being approved for life-saving surgery, time is quickly running out for the brothers.
- Liz has gone from being bedbound with lymphedemas on both legs, to standing and walking, but old fears are about to threaten her progress. And if Jenn and Marissa can't get along as mother and daughter to lose weight, they'll have to proceed apart.
- 20 years after her dad died as a result of a botched weight loss surgery, Carrie is on the brink of eating herself to death. To live, she must face the fear and grief of losing her father and end a cycle of toxic behavior with her husband Chris.
- Olivia strives to weigh-in under 200-lbs as she lives by herself for the first time and suffers an unexpected loss. Battling a series of let downs, James fights to reach his goal of skin surgery and to live a fulfilling relationship for the first time.
- Charity weighs nearly 800-lbs. Suffering from flesh-eating bacteria and butterfly shaped fat deposits; she is unable to function without help form her family. When unexpected bad news threatens her weight loss journey, she must decide if she can continue.
- At 700 pounds, Chad's weight is dangerously out of control. After gastric bypass surgery, he quickly sheds pounds but faces a medical crisis when he does not follow the doctor's orders. In dire straits, Chad puts his weight loss journey on the line.
- Dottie loves being a mom but, at over 600lbs, she's on the verge of leaving her 2 young children motherless. She agrees to a drastic new diet, but her child's life-threatening emergency & her own self-sabotage threaten to derail all hopes for weight-loss.
- At over 700lbs, Teretha's life is confined to a bed which is a far cry from her former job representing Detroit's healthy eating program. Her adoring family fears losing her and hopes a gastric bypass will provide the solution she needs to save her life.
- Pauline must find the will to keep up her weight-loss progress after a medical emergency. Chaye's finally admitting what he's long known, that he's a transgender woman. However, the emotional stress of coming out could threaten his weight loss journey.
- Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her. Will weight loss surgery be able to fix her fertility issues as well as her marriage?
- Since the death of his mother, Aaron has lived at home to care for his aging father. But due to his food addiction, Aaron has to heavily rely on his father for help instead. Now, Aaron must learn to care for himself to avoid eating himself to death.
- Krystal began overeating to shield herself with a protective layer of obesity after suffering years of abuse. Once a means of protection, her pathological eating now threatens to destroy her life if she doesn't get help.
- Away from Dr. Nowzaradan's care, Penny has returned to Maryland believing she can make the right choices to lose weight, but has she truly changed? Dating for the first time in her life, Tara continues to lose weight and is learning to balance new roles.
- At just 24, Bettie Jo is eating her way towards 700-lbs. Housebound, she is reliant on her husband for even basic needs. Bettie Jo's future relies on her losing weight, and her husband losing his fear that if she loses weight, she will leave him.
- Laura has used food to cope with her emotions for too long. Confined to a wheelchair, relying on an oxygen tank to breathe, she depends upon her husband and mother to survive. Love for her family must conquer her demons if she is to turn her life around.
- After overcoming a dependence on drugs & alcohol, sneaking food is 660-lb Doug's last remaining vice. Can this husband, and father of 3 overcome his addictive personality and take control of his eating habits in order to save his life and his marriage?
- At 661 lbs, Erica regrets not keeping a promise to her mom. She hopes her siblings will help but they are reluctant based on her past failures. Each meal threatens Erica's worst fear coming true; dying the same way she lives, alone and surrounded by food.
- Dr. Nowzaradan is worried Lupe's emotional issues are blocking her weight loss journey since she's shed over 300-lbs but still can't walk... And when Ashley is struck with sudden paralysis, her own emotional stability is thrown into peril.
- A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again.
- Liz is completely bed bound with severe lymphedema that makes it impossible to walk. Utterly isolated, with no friends, she battles depression, and lives with her mom who is too ill to take care of her. Liz desperately wants to become mobile.
- Born as 'Matthew', Destinee never felt like she fit in. Now, having come out as a 600 pound transgender woman, she likes her curves, but she will need to say goodbye to them if she wants to be approved to transition completely.
- Joyce needs home health care 24/7 and hasn't left the house in 3 years. But getting to Dr. Now in Houston is just the first step, and when he prescribes therapy where Joyce must revisit an unhappy past with her mom, it might be more than she can handle.
- Alicia's relationship with her boyfriend comes under the microscope in the second year of her weight loss journey; now in her fourth year, Pauline must beg her way back onto the program after quitting when her last weigh-in didn't go so well.
- At nearly 1,000 pounds, Samantha is dangerously close to dying. To make matters worse, she's paid to eat by making videos online. If Samantha doesn't overcome her toxic relationship with food, she worries that she will leave her daughter motherless.
- Love motivates 660-lb Donald to begin his weight loss journey.
- At 600 pounds, Lupe spent the last 10 years in bed & totally dependent on her husband. A doctor in Texas is her only hope for change. A cross-country move to save her life, may end up backfiring. Did Lupe wait too long to begin her weight-loss journey?
- Melissa finds herself overwhelmed with four children, a marriage on the rocks, and an unexpected pregnancy. When Ashley's weight loss journey hits a wall, she sets out to find new inspiration to get herself back on track towards a healthy lifestyle.
- Bettie Jo battles depression and a cancer diagnosis and when she finds out she's pregnant, she and her husband must find a way to cope. Susan suffers a major setback after surgery for her excess skin, thwarting her hopes to conquer her obesity.
- Robin and her brother Chris are both obese and already lost a sibling to obesity. They plan to visit Dr. Now together when Chris suffers a stroke and can't go. Luckily for Robin, Chris's son Garrett, already 600lbs at age 20, is game to join the journey.
- Kenae' was already big before her weight gain took off after the death of her beloved mother. Refusing to deal with the pain, Kenae' turned to food to fill the void. But she'll be reunited with her mom soon if the denial continues.
- Mark sets out with a goal for weight loss surgery, but as weight loss gets easier, he turns down medical advice and decides to do it on his own. Now, Mark thinks he can lose 500 pounds by himself, but Dr. Now sees this as another excuse not to change.
- 600-pound June copes with the tragic death of her son by eating. After gastric bypass surgery, she must confront the emotional issues driving her food compulsion. If she can stay on track, she can become the mother she desperately wants to be.
- Cynthia is a 610-lb single mother raising five kids. She's been focused on her children, but now realizes what her death would mean for them. As she battles her emotions and the pressures of life, she is forced to fight even harder to save her own life.
- Diana, a once thin and active woman, is now a prisoner to her 620lb body. Desperate to break free of her food addiction, she trades the comfort of her apartment for a weight loss journey under the strict authority of her niece in order to regain her life.
- Holly already has one failed weight loss surgery, so to succeed this time, she must do more than change her eating habits, she must address the childhood issues that continue to plague her.
- At over 600-lbs, Angie is trying to get to Houston to see Dr. Nowzaradan, in hope of getting weight loss surgery to save her life. But family conflict and a disagreements may stop her from being able to do what she needs before she even gets the chance.
- Shannon's husband loves her the way she is, but that may not help because she's 700 pounds and bedridden. Dr. Now knows it's not easy to break a toxic cycle of overfeeding and enabling, but that's what needs to happen if Shannon wants to live past 40.
- When Nathan's weight gets in the way of the only healthy thing in his life - his job as a drama teacher - it's a wake-up call for him. But changing his life might mean a falling out with his wife, Amber, who is also overweight, unless she can lose, too.
- Michael's massive 632lb body has left this husband and father dependent upon his family. If he doesn't learn to control his anger issues around food, lose weight, and address the root of his issues, then he will remain in jeopardy of losing everything.
- Weighing over 700-lbs, Nicole is on the verge of leaving her two young children motherless. Trying to survive a family of addicts, she commits to Dr Nowzaradan's diet program, but crisis threatens to derail all her hopes for weight-loss.
- Weighing 791-lbs, James is bedridden, unable to stand, and can barely move his legs. He may only have a few months to live, so his family takes a high-risk journey to Houston, TX with the hope that bypass surgery can save his life.
- 2012– 1h 25mTV-145.9 (48)TV EpisodeSteven Assanti weighs nearly 800-lbs and his brother/nemesis, Justin, is almost 600-lbs. Though the brothers can't stand each other, their father packs up the family to travel across the country to seek help, desperate to save both his sons' lives.
- Surgery enables Teretha to return to family in Detroit, but it soon threatens to undo all her progress. Trucker Chad is back on the road, but his old diet is a risk.
- When Travis got too big to walk down the aisle, he promised to give his wife a proper wedding one day. Since then he's only gained weight. Now, Dr. Now is Travis's only hope to lose weight and get the life he and his wife dreamed of having together.
- Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy. But Randy falls ill, and Lisa is about to find out if she has the will and determination she needs in order to turn her life around.
- At nearly 700 lbs., 51-year-old Pauline has an addiction to food that is killing her and taken over the life of her son, who is the primary caretaker. Can she overcome this addiction to change her lifestyle and save both their lives?
- Gastric surgery freed Brittani from her housebound life, but to achieve her ideal body she'll have to endure two more painful surgeries. Sean's super-obesity nearly killed him... Will he finally make a break from his mother's over-protective care?
- Lacey ballooned up over 600 lbs on pizza and ice cream and knows Dr. Now is her best hope for success. She must now rally her divorced parents around her for support and find a way to modulate her moods that won't include binge-eating.
- Octavia has been bedbound for nearly a year when she decides to make the trip to Houston to get help from Dr. Now, but when it turns out that her best friend is also her worst enabler, Octavia will have to choose between old habits and a new life.
- Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend Christian. But when Christian decides he's had enough and leaves Maja high and dry, she will discover that the only person she can count on is herself.
- Dominic's life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only Dr. Now can help him learn to face his life challenges without using food to cope.
- Devastated by the sudden loss of her son, Dottie's weight loss journey is in danger of going off track. June embarks on a plan to win approval for skin surgery. And Melissa, Jessica and Matt prepare for skin removal surgery.
- Charity's daughter becomes dangerously obese; devastated by the death of her husband, Elroy, Milla must find a way to finally qualify for gastric bypass; checking in with individuals who underwent skin removal surgery.
- When Angela's family is unable to accompany her on her weight-loss journey to Texas she is unsure what to do. At the last minute, she reaches out to an old flame, Eric, who still has love for her and is willing to make the trip.
- At 600 lbs, Ashley had to move home so her mom can help her care for not just herself but her newborn daughter. Now Ashley must overcome a lifetime's worth of unfortunate circumstances and get Dr. Now's help to find a way to go on living.
- Cindy is resistant to change and has spent years creating a world that makes her feel safe. When her friend notices Cindy's health declining rapidly due to her size, she pushes Cindy to move to Houston and see Dr. Now. But Cindy isn't so easily persuaded.
- Having her daughters help bathe her is not how Chrystal pictured parenting but she is so large that there's no other option. Chrystal wants Dr. Now's help but she didn't know that bringing her childhood trauma to light would be part of the deal.
- Bedridden for four years, 46-year old Penny knows that her weight may kill her if drastic actions aren't taken. Penny moves from Maryland to Texas, to have gastric bypass - but her unwillingness to make real lifestyle changes could be her downfall.
- Marla is so heavy she cannot stand up. Bedridden, her true weight is unknown but estimated at 800-lbs. Marla must face the facts about her health and the toll it takes on her supportive family if she is to save her health.
- Despite having lost 378 pounds, Angel's crippling knee pain combined with a legacy of extreme obesity threatens everything she's worked for.
- Joe was once 800lbs, housebound and alone. Now engaged, can he continue his weight loss? Pauline is on the verge of independence if only she can qualify for the skin surgery she needs so badly.
- Surgery enabled Laura's independence but the complications nearly killed her and she's terrified about the next skin surgery. Chay revealed to her family she was transgender but living life as an overweight woman; can she stick to her weight loss journey?
- A former plus-size model and "big is beautiful" advocate, Renee now realizes the mortal mistakes she has made as her weight swells to 600-lbs and her health crumbles.
- In year 3, Erica is succeeding on her weight loss journey when romantic misfortune sends her spiraling backwards; Benji Bolton must reach his goal weight without the support of his brother David, after a disagreement leaves the brothers estranged.
- Seana is 23 and nearly 700 lbs, living at her mom's house, depressed and anxious, her weight-gain threatens her livelihood. Dr Now can give her the tools she needs to live, but until she chooses life, no one can save Seana but Seana.
- Lisa's struggle with her weight began as a child and significantly worsened after witnessing her brother's murder. Now bedridden and unable to care for herself, Lisa must find a way to lose the weight or she will never see her grandchildren grow up.
- Weighing over 600 pounds, Kirsten is close to losing all her mobility. While she's trying to get control ofher obesity she's also in danger of losing her troubled son. Can Kristen lose the weight, regain her health,and learn to be a mother again?
- At 24 years old and over 600 lbs Megan lives at home with her mom who cooks for her since Megan can't do much on her own; Megan must travel to Houston to meet Dr. Now and change her eating habit or her life may end before it ever begins.
- Laura has lost 300lbs+ and is much less dependent on her husband Joey who now he's having trouble finding his way in the relationship. Marla, one of Dr. Now's most challenging patients returns and the fireworks begin all over again.
- For 23 years Leneatha has worked as a pharmacy tech at a local hospital; now she has a young daughter to support but she's so big that it is hard to move; if Dr. Now can't help her to stop eating, losing her job could be the least of her worries.
- Dottie faces an unexpected challenge to her weight-loss when her husband's drinking problem becomes intolerable for her and her son; Cynthia starts to wonder if being there for her kids at her current weight is more important than losing more.
- In order to keep pace with her daughter Charly's weight loss, Charity must do something she's never done: find a way to go it alone; try as she might, Teretha finds one too many obstacles in the way of continuing with Dr Nowzaradan's program.
- Tanisha weighs around 600-lbs and she's desperate to survive for her kids and avoid her mother's tragic fate of dying at age 50 from super obesity. Now at 32, her future looks grim if she doesn't make a drastic change to save her life.
- With severe lymphedema, Mercedes can barely stand and only cares for her 2 small children with the help of her extended family. Dr. Now can give her the tools to lose weight, but to succeed she must face the trauma inflicted by her late abusive father.
- Ashley is 24 years old and lives alone; her only source of comfort is food and the relationships she has online; but not a single one of her profiles are real; Ashley learns that Dr. Now isn't someone that she can lie to unlike her online friends.
- Krystal meets the man of her dreams but her chronic illness makes her fear becoming his caretaker, so she hesitates to accept his proposal until she's sure of her health.
- An athlete's career ends with a knee injury. Unable to exercise, he gains over 600 pounds. To lose weight, he must confront how severe his situation has become.
- A grocery run becomes life-threatening, forcing overweight Delana to get help losing weight from Dr. Now. She hopes this recovery will bring her and her distant daughter closer.
- Abi became obese before an accident left him unable to walk. Bedridden for years, his extreme weight is life-threatening. His only hope is Dr. Now's program for drastic weight loss and mobility.
- At 58, Rose had given up on life. But for her family's sake she resolves to lose over 400 pounds no matter what it takes.
- Recovering addict Charles replaces drugs with food. Morbidly obese, he needs Dr. Now but his brother enables his gluttony. Will he make the trek to Houston?