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A physicist, his wife and two mediums are hired to investigate the Belasco House, where 27 guests had inexplicably died in 1927, along with most of a team of paranormal investigators that was sent in the early 1950s.

Just when Michael arrives in Berlin to visit his ex-girlfriend Gabi, a terrible virus starts spreading across the city at a rapid pace, turning people into mindless homicidal maniacs. Much to Michael's concern, Gabi's not home; instead, he meets Harper, a teenage plumber's apprentice at work in her apartment block. Together, they manage to barricade themselves when raging hordes of infected people swarm the building. Surrounded by these thirsty zombies, Michael and Harper have their hands full to survive - and it will take all of their ingenuity to make their way out to try and find Gabi.