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A killer authors a book about his con-man past that becomes the key to solving a 29-year-old cold case of two high school sweethearts--and three other cold case murders--leading police to believe he could be the Zodiac Killer.

When 31-year-old real estate appraiser Mike Williams mysteriously vanishes while duck hunting in the Florida swamps in December 2000, authorities assume that he accidentally drowned in Lake Seminole. But the case is re-examined sixteen years later after the police receive a distress call from the victim's wife, Denise Williams.

The 1998 brutal murder of 36-year-old computer analyst Lisa Valdez inside her San Francisco studio condominium was a mystery until advances in forensic technology helped solve the case 13 years later. Her killer, Anthony Quinn Hughes, was finally brought to justice for her savage murder.

When Sherry Leighty goes missing in 1999, her family is left wondering how a dedicated mother of three could vanish without a trace. A decade later, the cold case heats up when Sherry's sister launches a social media campaign to help solve her sister's mysterious disappearance. An online tip unearths the truth and a sinister family secret.

When 25-year-old school teacher Christy Mirack is found brutally murdered in her Lancaster, Pennsylvania, apartment in 1992, there is no shortage of suspects. Twenty-six years after her murder, cold case detectives get a break when the sister of the killer uploads her DNA profile to a public genealogy website. This development leads to the arrest of a former disc jockey, Raymond Rowe (who performed under the name DJ Freez) who accepted a plea deal and admitted his guilt.

In the 1980s, a suspected serial killer preyed on women in small towns located on the banks of the Mississippi River until the murders abruptly ceased and went unsolved. In 2006, 26 years later, a cold case detective and producer on the set of "Cold Case Files" unknowingly began to connect the dots that would crack the case while discussing the murder of Deborah Sheppard, a Southern Illinois University student whose death had remained a mystery since 1982.

23-year-old teacher Irene Garza was a former beauty queen and devout Catholic who vanished the evening before Easter after giving confession. Residents of her close-knit border town did their best to find her, but after a series of false leads, her body was found floating in a drainage canal clearly the victim of a violent sexual predator. At the time, a key witness hinted that a member of the Catholic clergy may have been responsible, but the clue remained buried for 42 years until a former priest comes forward with a damning confession from another man of the cloth that reveals a sinister cover up.

Near what's known as the hanging tree, the mutilated body of Timothy Coggins is found in late 1983. The investigation stalls and goes cold for over 30 years, until a newly elected sheriff vows to bring the killers to justice, and he does.

In 1980, radio intern Helene Pruszynski is found brutalized in a snowy field; after 37 years of fruitless leads, investigators tap into a public genealogy website that leads them across the country to the killer they've been hunting.

On Easter Sunday of 1992, the body of missing woman Lisa Ziegert is found in a field; the investigation yields many leads, but no true suspect; after more than two decades on ice, the case is revived when DNA phenotyping puts a face to the killer.

Just after the last day of school in 1984, 15-year-old Reesa Trexler is found murdered in her grandparents' home; for decades, a stalled investigation only fuels the town rumor mill, pointing an accusing finger at Reesa's 13-year-old sister, Jodie.

When beloved Red Bank middle school teacher Jonelle Melton is found murdered in her Neptune City, New Jersey apartment in the fall of 2009, suspicion is cast on her soon-to-be ex-husband, who eventually helps solve the crime years later.

In 1972, the body of Jody Loomis is found in the woods. Thirty-four years later, the killer's DNA is recovered from Jody's old clothing, but it isn't matched until 2018 when genetic genealogy helps point to one suspect.

Two masked gunmen commit a violent robbery and shoot Michael Temple Jr. in 2015, rendering him a quadriplegic for five years before his death. In this unusual cold case, DNA from a knife is used to create a sketch of the killer.

Thirteen days after Pam Pitts disappears in 1988, her charred body is found at a popular hangout spot in the Arizona desert; when a second victim is discovered in a mine shaft, detectives suspect the killer may have known them both.

When 23-year-old Tonya McKinley is found brutally murdered on New Year's Day 1985, a boy is left motherless; a family waits 35 years for advancements in forensic science to finally catch a killer using familial DNA.

In late 1983, the bodies of five people abducted from a local fast food restaurant are found brutally murdered in an oil field. The main suspect is long believed to be a well-connected local man, until new evidence reveals the true killers had been hiding in plain sight for decades.

College student Brad Perry shows up to work his graveyard shift at the gas station and is never seen alive again.

Houston, Texas, March 1984. Jack Kennedy discovers his two adult daughters brutally murdered. Their mother and niece spend their lives keeping the case alive. DNA leads nowhere. Thirty years later, an informant gives up a name. But the ordeal for the family is far from over.

In July 1997, the brutal murder of 19-year-old Tiffany Johnston rocks the small town of Bethany, Oklahoma. DNA points to her killer over a decade later and leads investigators across state lines to Texas, and the buried bodies of two other missing women.

In July of 1970, the brutal murder of single mom Loretta Jones leaves four-year-old Heidi Jones motherless. Nearly 40 years later, Heidi vows to solve her mother's cold case and calls on an old high school friend to help her find justice for Loretta.

Lauria Bible and Ashley Freeman, both 16, disappeared after a mobile home fire in 1999, and Ashley's parents were found murdered inside the home in rural Oklahoma. investigators suspect foul play and it sends a mother on a decades-long crusade to find out what happened to her missing teenage daughter and best friend.

June 1985: 20-year-old "Sucker Day" Festival Queen Jackie Johns has gone missing, and soon her body is found in Lake Springfield. The small community of Nixa, Missouri, is certain her blood is on the hands of a local wealthy businessman, Gerald Carnahan, but it takes 25 years and the advent of DNA testing to find the true killer.

When human bones are discovered in the woods in Schuylkill Haven, Pennsylvania in December 1985, it puts an end to the search for missing 13-year-old David Reed; skull fractures point to murder, but it will be decades before investigators can find David's killer. One person of interest is Joseph "Joe" Geiger.

Everett, Washington firefighter Gary Parks is killed in an arson fire at Everett Community College on Feb 16, 1987. A serial arsonist is thought to be the culprit, but it will take a dogged detective to find the killer. One suspect is Elmer Nash Jr of Snohomish, WA.