- Has tattoo that says "Mom Rest in Peace; Dad Rest In Peace."
- Regarded as one of Florida's top three defensive linemen after the 1999 season.
- The Patriots drafted him with the 21st overall pick in the 2004 NFL Draft. In his rookie season with the Patriots, he compiled two sacks, 27 tackles, and three deflected passes. He saw considerable playing time during his rookie season, and helped the Patriots get back to the Super Bowl against the Philadelphia Eagles in February, 2005.
- Starting Defensive Tackle for The New England Patriots. (November 2005)
- Wilfork is a cousin of C.J. Jones, the defensive tackle of Houston Texans, wide receiver Anquan Boldin of San Francisco 49ers, Florida based bassist Sylvester "Tre" Banks III and was cousin of Corey Jones.
- [announced his retirement.[August 2017].
- Has an endorsement deal with Kingsford, a charcoal company.[August 2017].
- He also has endorsements with Castrol, Motor Oil, and Williams-Dickies Overalls.
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