- Sister of former US President John F. Kennedy and senators Robert F. Kennedy and Ted Kennedy, Jean Kennedy Smith, Patricia Kennedy and Rosemary Kennedy.
- Founded the Special Olympics in 1968.
- Mother-in-law of Arnold Schwarzenegger.
- Her brother Ted Kennedy passed away 15 days after her death. With his death, Jean Kennedy Smith remains the last surviving child of the American political dynasty that was created by the marriage of Joseph P. Kennedy and Rose Kennedy.
- She was the first living American woman to be portrayed on U.S. legal tender (the Special Olympic coins of 1995).
- She predeceased her brother Senator Ted Kennedy, who was too ill to attend her funeral, by 14 days.
- Fifth of nine children of Ambassador Joseph P. Kennedy with Rose Kennedy.
- Daughter of Joseph P. Kennedy and Rose Kennedy.
- Aunt of Christopher Lawford.
- Inducted into the National Women's Hall of Fame in 1998.
- With the death of Rosemary Kennedy on January 7, 2005, she is the oldest living child of Joseph P. Kennedy and Rose Kennedy.
- Grandmother of Katherine Schwarzenegger and Patrick Schwarzenegger.
- Irish-American.
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