- She's also a trained opera singer. She sang the role of Rosalinde in Michael Thalheimer's 2007 production of 'Die Fledermaus'.
- She's fluent in English and French.
- Ambassador of Terre des Femmes, fighting against female genital cutting.
- She's the daughter of actress Heidemarie Rohwedder and Willi Hoss, co-founder of the German Green Party.
- Plays the piano. Did her own playing in Barbara (2012).
- Sang guest vocals on "Europa Geht Durch Mich" by the Manic Street Preachers, from the album 'Futurology' produced by her partner. (2014).
- She declined a starring role in Germany's long-running crime drama series Tatort (1970).
- Her favourite directors include John Cassavetes, François Truffaut, Jean-Luc Godard and Claude Sautet.
- Interviewed in 2015, she named her Top 10 movies as: Breaking the Waves (1996), The Celebration (1998), Contempt (1963), The Deer Hunter (1978), Dirty Hands (1975), La Notte (1961), Opening Night (1977), The Silence (1963), Traffic (2000) and A Woman Under the Influence (1974).
- Made her stage debut at the age of 14.
- Graduated from the Drama School "Ernst Busch" in Berlin (1997).
- Has been ensemble member at the Deutsches Theater in Berlin since 1998.
- Her acting models include Gena Rowlands, Romy Schneider, Ingrid Thulin, Jeanne Moreau and Catherine Deneuve.
- On the 10 February 2015, she was awarded the title of 'Chévalier' of the French Order of Arts and Letters. Other honorees included actress and producer Manuela Stehr (also knighted) and Nina's frequent stage collaborator, director Thomas Ostermeier (who was raised from Officer to Commander).
- She's known to be an extremely humble person. At the 2007 Berlin film festival, while accepting her Silver Bear for her performance in Yella (2007), she stated that the award should have gone to Marianne Faithfull for Irina Palm (2007).
- Member of the Jury of the Locarno International Film Festival in 2009.
- Married longtime partner Alex Silva in 2015, although she didn't reveal it until five years later.
- She's a fan of Breaking Bad (2008).
- 2000: Named as one of European films 'Shooting Stars' by European Film Promotion.
- Respected stage actress in her role as "Buhlschaft" at the Salzburg Theatre Festival (2005).
- She was part of the Michael Powell Jury at the 2014 Edinburgh Film Festival.
- Learned how to shoot a rifle for We Are the Night (2010).
- Hobbies include jazz-dance, hiking and camping.
- She was nominated for the 2010 Faust Award for Best Acting performance for her work in 'Oil'.
- She won the 2006 'Gertrud-Eysoldt-Ring' award for her stage performance in Medea.
- Learned how to ride a horse for Gold (2013).
- For her performance in Yella (2007), she was one of three consecutive German winners of the Silver Bear for Best Actress at Berlin Film Festival: she was preceded by Julia Jentsch in Sophie Scholl: The Final Days (2005) and Sandra Hüller in Requiem (2006).
- She provided the voice of Louise (Emmanuelle Béart) in the German dubbed version of 8 Women (2002).
- Has been engaged to actor Hans-Jochen Wagner (1995-2002).
- She starred in seven movies that were screened in competition at Berlin Film Festival: Elementarteilchen (2006), Yella (2007), Barbara (2012), Gold (2013), Return to Montauk (2017) , My Little Sister (2020) and Langue Étrangère (2024). She won the Silver Bear for Best Actress for "Yella".
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