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- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoAspiring film actress Penny moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.
- CreatorTrey ParkerMatt StoneBrian GradenStarsTrey ParkerMatt StoneIsaac HayesFollows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- CreatorJames L. BrooksMatt GroeningSam SimonStarsDan CastellanetaNancy CartwrightJulie KavnerThe satiric half-hour adventures of a working-class family in the misfit city of Springfield.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorDavid X. CohenMatt GroeningStarsBilly WestJohn DiMaggioKatey SagalPhilip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.
- CreatorBill LawrenceStarsZach BraffDonald FaisonSarah ChalkeIn the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- CreatorLee AronsohnChuck LorreStarsJon CryerAshton KutcherAngus T. JonesA hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- CreatorAlan BallStarsAnna PaquinStephen MoyerSam TrammellTelepathic waitress Sookie Stackhouse encounters a strange new supernatural world when she meets the mysterious Bill Compton, a southern Louisiana gentleman and vampire.
- CreatorTim KringStarsJack ColemanHayden PanettiereMilo VentimigliaCommon people discover that they have super powers. Their lives intertwine as a devastating event must be prevented.
- CreatorBryan FullerStarsEllen MuthCallum BlueJasmine GuyGeorgia Lass is surprised to discover that an afterlife does exist, and that she's already been assigned a job. Her new boss is Rube, a "reaper" -- one of the many who pluck the souls of the living and escort them to their eternal reward.
- CreatorEric KripkeStarsJared PadaleckiJensen AcklesJim BeaverTwo brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- CreatorChris DowneyJohn RogersStarsTimothy HuttonGina BellmanChristian KaneNathan Ford and his five-member team of thieves and hackers come together like modern-day Robin Hoods in an attempt to steal from rich and powerful individuals who take advantage of others.
- CreatorTom KapinosStarsDavid DuchovnyNatascha McElhoneEvan HandlerA writer tries to juggle his career, his relationship with his daughter and his ex-girlfriend, as well as his appetite for beautiful women.
- CreatorFrank DarabontStarsAndrew LincolnNorman ReedusMelissa McBrideSheriff Deputy Rick Grimes wakes up from a coma to learn the world is in ruins and must lead a group of survivors to stay alive.
- CreatorDan HarmonStarsJoel McHaleDanny PudiDonald GloverA suspended lawyer is forced to enroll in a community college with an eccentric staff and student body.
- CreatorAaron KorshStarsGabriel MachtPatrick J. AdamsMeghan MarkleOn the run from a drug deal gone bad, brilliant college dropout Mike Ross finds himself working with Harvey Specter, one of New York City's best lawyers.
- CreatorTerence WinterStarsSteve BuscemiKelly MacdonaldMichael ShannonAn Atlantic City politician plays both sides of the law by conspiring with gangsters during the Prohibition era.
- CreatorVince GilliganStarsBryan CranstonAaron PaulAnna GunnA chemistry teacher diagnosed with inoperable lung cancer turns to manufacturing and selling methamphetamine with a former student to secure his family's future.
- CreatorJason SmilovicStarsChristian SlaterMike O'MalleySaffron BurrowsHenry Spivey, an efficiency expert, lives a typical suburban life, right down to the wife, two kids, dog, and minivan. In contrast, Edward Albright is a lethal, multilingual operative. It would seem the two men have nothing in common -- except for the fact that they inhabit the same body. When each personality finds himself out of his element, things go awry.
- CreatorShawn RyanStarsMichael ChiklisMichael JaceJay KarnesFollows a gang of corrupt Los Angels Police Department (LAPD) cops called The Strike Team, who uses illegal methods to maintain law and order, whilst engaging in a series of undercover dealings secretly in order to get rich.
- CreatorShonda RhimesMichelle LirtzmanStarsEllen PompeoChandra WilsonJames Pickens Jr.A drama centered on the personal and professional lives of five surgical interns and their supervisors.
- CreatorDavid ShoreStarsHugh LaurieOmar EppsRobert Sean LeonardUsing a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- CreatorChris FedakJosh SchwartzStarsZachary LeviYvonne StrahovskiJoshua GomezWhen a computer geek inadvertently downloads critical government secrets into his brain, both the CIA and the NSA assign an agent to protect him and exploit his newfound skills.
- StarsChris O'DowdRichard AyoadeKatherine ParkinsonThe comedic misadventures of Roy, Moss and their grifting supervisor Jen, a rag-tag team of IT support workers at a large corporation headed by a hotheaded yuppie.
- CreatorRob GrantDoug NaylorStarsChris BarrieCraig CharlesDanny John-JulesThe adventures of the last human alive and his friends, stranded three million years into deep space on the mining ship Red Dwarf.