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- Shin Dong-Huyk was born on November 19, 1983 as a political prisoner in a North Korean re-education camp. He was a child of two prisoners who had been married by order of the wardens. He spent his entire childhood and youth in Camp 14, in fact a death camp. He was forced to labor since he was six years old and suffered from hunger, beatings and torture, always at the mercy of the wardens. He knew nothing about the world outside the barbed-wire fences. At the age of 23, with the help of an older prisoner, he managed to escape. For months he traveled through North Korea and China and finally to South Korea, where he encountered a world completely strange to him.
- The feature doc takes a look behind the scenes at top-class restaurants and offers exclusive interviews with celebrity chefs from France, Spain, Germany, the Netherlands, Denmark, the USA and Japan.
- The general objective of the LifeValve project is to develop a new therapeutic strategy to treat heart valve disease. In particular, the development of a tissue engineered living heart valve, with the capacity of growth in accordance with the growths of children, which can be implanted without an operation by using minimally invasive catheter technology. The reason for first focussing on paediatric applications is twofold: First, a novel, tissue engineered living heart valve with the potential for growth is addressing a clearly unmet medical need in congenital heart disease. All contemporary solutions with conventional heart valve prostheses are insufficient, do not provide a sustainable treatment and as a consequence create suffering and substantial socioeconomic costs. Second, successful use and increasing clinical experience within the paediatric patient population as entry indication will allow extending the clinical application to the much larger adult patient population with degenerative heart valve disease in a later stage of the project.
- Dogs are more than man's best friends; they can help us unravelling the genetic of diseases such as cancer, epilepsy, cardiovascular troubles, diabetes etc. Living in the same environment, human and dogs are suffering from the same diseases but the genetic complexity is quite lower in dogs. During 4 years 20 veterinary schools spread across Europe are working together to collect 10.000 blood samples from purebred dogs affected by similar diseases as human. The analysis of the genome of affected dogs compared to healthy ones of the same breed lead to the identification of genes implied in the mechanisms of these diseases. This research will help reducing the high level of inherited disease in purebred dogs and will allow a better understanding of the mechanisms and pathways of pathologies. Human medicine will ultimately benefit from these results. That is why the project is called LUPA as the female-wolf feeding the twin founders of Roma reflecting the benefits humans will obtain from dog genetics.
- 24 hours that changed the world: On November 9, 1989, Günter Schabowski, member and spokesman of the Politburo of the Central Committee of the SED, read out the GDR's new travel regulations at a press conference broadcast live on GDR television. It had been drawn up by high-ranking officers from the Ministry of the Interior and the State Security. Contrary to the guidelines of the political leadership, the authors had written the possibility of an unbureaucratic departure and re-entry into the paper. Nevertheless, the travel regulation passed the Central Committee without objection.
- MOSAR aims to significantly advance our knowledge of the control of antimicrobial resistance in bacteria responsible for severe and emerging nosocomial diseases in hospitals and now spreading into communities.
- Despite large coverage with efficacious vaccines, whooping cough is still a major cause of global childhood morbidity and mortality. In an effort to solve this problem, the Child-Innovac programme has developed a new vaccine designed to be given as a single dose at birth in order to protect young children, under 6 months of age, which is the most vulnerable age group and not sufficiently protected by the current vaccines. The new vaccine is based on a novel concept of nasal administration of the live genetically attenuated whooping cough agent, which in pre-clinical animal tests has been shown to be perfectly safe and able to induce strong, rapid and long-lasting protection against the infection. Within the frame of the Child- Innovac project, this vaccine will now be administered for the first time to man. If successful, it will constitute a novel platform to vaccinate by nasal administration against a number of different respiratory infections and other diseases.
- The prevalences of obesity, Type 2 diabetes and the metablic syndrome are rising rapidly both in Europe and worldwide. There is evidence that this is due to the population taking less exercise and becoming more sedentary, coupled with the increased consumption of high fat, low fibre foods (fast food or convenience food). The EXGENESIS consortium aims to provide insights into the reasons why poor diet and lack of exercise contribute to increasing levels of obesity and diabetes.
- To establish biomarkers of human ageing, 26 groups in 14 European countries have joined forces in the "European Study to Establish Biomarkers of Human Ageing (MARK-AGE)".
- The central aim of the MetaHit project is to establish associations between the genes of the human gut microbiota and human health and disease.