Sheldon and Dr. Linkletter struggle to solve an equation; Georgie has a solution for Meemaw's business woes; George Sr. gives advice on Missy's love life.
Sheldon battles President Hagemeyer's mysterious boss over the university's science requirements; Mary discovers that Georgie is working at Meemaw's illegal gambling room.
Sheldon gets an odd request from an old friend, Paige. Also, George Sr. and Mary are caught in the middle of Meemaw and Dale's breakup, and Georgie comes clean to Mandy.
Sheldon struggles to cope with the first signs of puberty, Mary and George Sr. both hunt for new jobs, and Georgie and Meemaw take a business trip across the border.