Director Paul W.S. Anderson and the crew traveled to remote locations in South Africa and Namibia to capture the film's expansive vistas.
Director Paul W.S. Anderson cast his wife Milla Jovovich as the lead in Monster Hunter following the success of their previous collaborations on the Resident Evil film series. This was the sixth time Anderson directed Jovovich in leading roles, after four Resident Evil films and one Three Musketeers movie.
Tip 'T.I.' Harris says that his youngest son convinced him to hop on board, because he is a fan of the video games.
The latitude and longitude of the UN zone places the characters in Afghanistan, proximal to Kabul.