The film wasn't announced by trade publications until after college students spotted Kristen Stewart filming on their campus in New York City.
Kristen Stewart and Glenn Close were in The Safety of Objects (2001) together in 2001, which was Stewart's first credited film role. It took 13 years for another collaboration in "Anesthesia."
Glenn Close and Sam Waterston worked together previously in the Broadway play "Benefactors" in 1985.