This is the second live-action adaptation of Hirohiko Araki's work, after JoJo's Bizarre Adventure: Diamond Is Unbreakable - Chapter 1 (2017).
Voice actor Takahiro Sakurai, who voices Rohan Kishibe in the animated "Jojo Bizarre Adventures" and "Thus Spoke Rohan Kishibe" features, has a voice cameo in each episode.
Voice actor Fairouz Ai, who voices Jolyne Kujo in JoJo's Bizarre Adventure (2012), has a voice cameo in the second season episodes.
This is the second adaptation of the This Spoke Rohan Kishibe series. The first one was a series of OVAs done by David Production and Warner Brothers Japan.