- A patient whose relative has called in a favor with Cuddy presents with nonspecific minor symptoms that turn life-threatening, but House is distracted by a dream and an inability to urinate.
- Soldiers are riding in a jeep through a desert, joking and listening to rock music. The music is cut off and they are attacked. One soldier runs up to one lying on the ground wounded, giving him a weapon, and runs off. The wounded soldier on the ground is House - at which point he awakens from the odd dream. Cuddy gives him a file for a "boring" case of someone who is related to a hospital donor - but House is immediately gripped because the file picture is the soldier who gave him the weapon in his dream.
The team is surprised that House has taken a case of vague Gulf War symptoms - joint pain, fatigue, etc., which they say can be found statistically in any large group of people. Wilson is intrigued by House's dream. House, meanwhile, is secretly striving to figure out where he's seen the guy before, so he orders the team to get a lengthy history, including television appearances.
During the team's interview, the patient, John Kelley, realizes that they do not believe his symptoms. He states that he doesn't care what they call it, Gulf War Syndrome or whatever, he just wants them to find out what it is so they can cure it.
Sleep apnea could cause fatigue, so a sleep observation test is ordered. Since it is proving uneventful, Cameron coaxes Chase into occupying another bedroom with her. When Foreman arrives in the observation room, Kelley is shouting for help. He smells something horrible, and Foreman sees that he has a nasty infection in his mouth. Disheveled, Cameron and Chase arrive on the scene. Later, Foreman asks where they were, and refutes a claim they went out for coffee by noting they didn't have any when they came in. Cameron coolly confesses that they were having sex, causing Foreman to laugh at the ludicrousness of the idea.
Suspecting cancer, Wilson biopsies Kelley's salivary glands, but the results show nothing. House asks Wilson for a prescription because he hasn't urinated in 3 days. Wilson blames the Vicodin, which House has no intention of stopping.
Chase tells Cameron that he doesn't want to lose his job over their sexual relationship, and will not do it at work anymore. Cameron says fine. Then flirtatiously asks him if he wants to go to lunch.
During additional tests by Wilson, Kelley unexpectedly loses his hearing. The results show cancerous growths in Kelley's brain. Cameron and Chase, returning from their "lunch", advise House that they have taken a history back to Kelley's great grandfather, including his uncle's nosebleeds. Wilson freaks that House has them researching his dream, and drags the team away.
Later, ready to drill into Kelley's skull for major work on his brain, Foreman notices that the O.R. brain scans are clear - the growths are no longer present. Cuddy produces scans from the VA, showing that the growths were not present before. Still immobilized for the procedure, Kelley begins shouting that he has lost feeling in his legs. Appearing concerned, House bends over him, and shouts, "Have you ever been in a porno?!"
House orders the team to observe the patient for changes, and astonishes them by going home to sleep. Anxious for some bladder relief, he painfully catheterises himself and crawls into bed.
Back and the hospital the team is still concerned about exposure to depleted uranium in the war zone. Despite House's orders against it, they decide to treat him for that. The numbness starts creeping up Kelley's body, and when it reaches his diaphragm he will need to be put on a respirator.
House spends sleepless hours in bed, then returns to work. He is furious that the team introduced a new treatment, since now they will not know if that is affecting Kelley's symptoms.
Kelley is now pale and losing blood, probably internally since there is none externally. At the patient's bedside, as House goes for equipment to start a transfusion, yellow fluid appears on the floor. Chase bends down and discovers it is urine. He looks at House and sees a bag attached to his leg, gushing fluid, and everyone is astonished. House defiantly asks if they've never seen a urine catch bag before.
Suddenly House's nose starts to bleed. He puts his hand up to it, thoughtfully looks at it - and wakes up in his own bed, covered by a wet sheet. The catheter is on the floor, and he has slept quite a few hours.
He returns to the hospital and looks in Kelley's nose. It is dry and hairless. He points out to the team that Kelley's nose must have been cauterized when he was a kid, probably to prevent the nosebleeds that his uncle also suffered. This is a manifestation of an inherited illness, Osler-Weber-Rendu syndrome (hereditary hemorrhagic telangiectasia), which also explains each of Kelley's other problems. House explains how each area can be treated and cleared up to relieve Kelley's symptoms.
Confronting Cuddy, House has finally realized where he saw Kelley before. A hospital benefit years ago, with his tongue down Cuddy's throat! Cuddy admits she didn't want to tell him because of the things he would say. But she also says it bothered House because he was jealous, and smugly tells House to get over her.
Cameron and Chase are in the janitor's closet, celebrating. Chase has just torn off his shirt when House bursts into the room, brushes between the two of them to throw away some papers, and walks out again.
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