One of the rare times the Luthor home in Metropolis is shown, albeit only the interior. The mansion in Smallville was said to be just keepsake that Lionel purchased and never visited before forcing Lex into exile there.
According to Martha, Clark's first word was "Lara", the name of his Kryptonian biological mother as revealed in "Memoria".
John Schneider was busy prepping for his directorial debut on the series, the next episode "Talisman". As a result, he didn't appear in this episode.
Interesting to note that even though this episode is clearly Lex-centric, Lionel has the most screentime in this episode, and it is the first episode in the series in which Lionel does have the most screentime.
At the beginning of the episode, young Lex is seen at the Excelsior Academy. "Excelsior" is a noted phrase (and possibly a nod) to comic legend Stan Lee (from Marvel Comics).