Ham was the name of the first chimp in space. He was launched from Cape Canaveral on January 31, 1961, and returned to Earth unharmed except for a bruised nose.
Comet's laptop computer has a banana logo on the top, an obvious parody of Apple computers.
Andy Samberg's first time voice acting in a theatrical film. Later, he'd go onto voice Brent McHale in the Cloudy with a Chance of Meatballs films, Jonathan in the Hotel Transylvania films, Junior the stork in Storks (2016), Dale the Chipmunk in Chip 'n Dale: Rescue Rangers (2022), and Ben Reilly in Spider-Man: Across the Spider-Verse (2023).
This is the only Space Chimps film to be released theatrically and be rated G by the MPAA. All others were straight-to-dvd and rated PG by the MPAA.