The building used for the setting of the hospital (externally) is actually a residential property on Scarborough's south cliff esplanade. It's split into flats and cottages.
Scott Taylor, who plays ambulance driver Frankie Robinson, is an ambulance driver in real life.
The house used for Dr Ormerod and Dr Wetherill's home is a residential property situated directly opposite St Mary's Church in Scarborough and has panoramic views of the North Bay from its garden which can be seen in an episode where they have a garden party.
Robert Daws (Dr. Gordon Ormerod) & Wendy Craig (Matron) also worked together on episode 5.5, Lost Identity (2016), of Death in Paradise (2011) as John Green / Marcus Knight & Mary Goodman respectively.
Sister Brigit would be required by religious convention to take on a new name as a part of her life as a member of a convent, seen as embarking on a new relationship with God. Her given baptismal name is Aisling.