The house used in the film is located in Grantham, England, and is owned by the University of Evansville (Indiana). It is used by students that study abroad.
Stephen King wrote the first draft of the script. When this fell through, he re-worked it into Rose Red.
Liam Neeson nicknamed Catherine Zeta-Jones "The Welsh Gazelle", because they repeated a running take time after time, and he couldn't keep up with her.
This isn't a remake of Robert Wise's classic, as the production company did not have the remake rights. They were not allowed to replicate even one shot from the 1963 film. Instead, it is a new adaptation of Shirley Jackson's novel.
The tagline for this movie "some houses are born bad" is also a line that Dr. Joyce Reardon says in the Stephen King made-for-television series Rose Red (2002).