Pig skin and offal from a butcher were used for the autopsy scene.
Franca Stoppi replaced another actress who was originally cast as Iris, and she signed on to act in this film without reading the script beforehand. On working with Joe D'Amato, actress she recalled him saying on set that "We're making a movie to make people throw up. We must make 'em vomit!"
Inspired the lyrics to the song "Deathmask Divine", by Michigan-based melodic death metal band The Black Dahlia Murder.
In Germany this horror film was on the index for 40 years and was confiscated several times.
Debut role and only career nude scene for Simonetta Allodi.