Volkswagen Bus en route to the crash site is not the same Volkswagen Bus that arrives through the gate at the crash site. VW badge is larger, chrome trim is missing and license plate is different.
When Victor Caroon's wife tries to get him out of the hospital, she and her friend Christie are standing outside in the rain, and you can clearly see that Christie's lab coat is getting wet. When he walks in the hospital, it is dry. He walks in and out a couple of times, but inside the hospital his lab coat is always dry.
When the spaceship is first seen, it is stuck into the ground at an angle of approximately 70 degrees, yet when Quatermass and his team enter, the inside is shown almost level.
Although the newspaper reports all refer to Q1's crash-landing as occurring on the previous night, the "News Chronicle" is dated Saturday October 23 1954 whilst the "Daily Mail" hails from Friday November 12 of the same year. Additionally, after the opening paragraphs, all of the reports are clearly about different subjects (such as a trade union dispute with BEA).
At the beginning of the movie a couple is walking down a lane and it is almost dusk, but still quite light. A moment later as they cross into the field it is definitely nighttime.
After verifying that the temperature on the crashed spaceship's hull was 300 degrees, there was no steam generated when the fireman sprayed the hull with water.
In some shots at Westminster Abbey, the wires guiding the creature's tentacles are intermittently visible.
At the crash site, in the engine compartment of the VW micro bus , there is radio equipment instead of an engine.
Despite the fact that Victor Caroon is obviously infected with some unknown alien fungus or disease, no precautions, such as wearing PPE, are taken by any of the medical staff treating him. Neither is he kept in secure isolation. This lack of precautions continues during following events. The dead chemist is examined with a lack of infection control. There is no attempt to protect the zoo workers as they collect the dead animal bodies. When Dr Briscoe collects the "living" sample at the zoo, he does so without any PPE, nor does he wear any when observing the specimen back in his laboratory.
When returning prior to finding the escaped creature on his floor, Gordon Briscoe appears completely unsurprised to find a Bunsen burner has been left flaming in the empty lab.
As Victor stumbles out of bed while his wife sleeps, a crew member is reflected on the glass doors.
Judith somehow deduces that the two nurses assigned to watch over her husband at the hospital are male nurses, despite being told only their last names.
Judith may have assumed the nurses were male because the night porter referred to them only by their surnames Jenkins and Tucker, rather than Miss/Nurse Jenkins or Tucker.
Quatermass pronounces "metabolic" as "meh-TAB-oh-lik".
When Quatermass is trying to turn the flywheel inside the rocket to open it, at first he turns it clockwise, which would tighten it. In the next shot he is seen turning it counter-clockwise with another man, which is correct.
Lomax is familiar with the track left by the Caroon creature, but fails to notice the large track at the entrance as he enters Westminster Abbey.