- Received a Bachelor of Arts degree from the University of Florida in 1993 and a J.D. degree cum laude from the University of Miami School of Law in 1996.
- His wife, Jeanette, is a former Miami Dolphins cheerleader and is of Colombian descent.
- Born in Miami, to Cuban parents who moved to the U.S. in 1956 as economic migrants.
- Republican candidate for U.S. Senate seat vacated by Mel Martinez.
- Member of the Florida House of Representatives (January 25, 2001 - January 2, 2009).
- Speaker of the Florida House of Representatives (January 2, 2007 - January 2, 2009).
- U.S. Senator (R-Florida) (January 3, 2011-January 3, 2023).
- Father of Amanda, Daniella, Anthony and Dominic Rubio.
- Father was a banquet bartender and mother was a cashier at K-Mart.
- Has three siblings.
- Member of the U.S. Senate Intelligence Committee, U.S. Senate Appropriations Committee, and the U.S Senate Foreign Relations Committee.
- Was featured in an episode of Finding Your Roots where he was discovered to have Native American ancestry. "One of your great-great-great-grandmothers was a pure Native American," host Henry Louis Gates informed the senator.
- U.S. Senate Intelligence Committee acting chairman [2020].
- U.S. Senate Small Business Committee chairman.
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