- A direct descendant of Charles Henri Sanson, public executioner of Paris, who beheaded Maria Antoinette and her husband King Louis XVI.
- The U.S. Airborne Ranger G.I. Joe was modeled on Ryan's father, Greg Sanson.
- Has two siblings: Older brother Garrett Sanson works alongside him on movies, oldest brother Matt is an Army Ranger.
- At the age of 13, Ryan became the youngest person ever to become a certified Professional Snowboard Instructor by the American Association of Snowboard Intructors (AASI).
- He studied at Improv Olympic in Hollywood for a short while, and now studies acting under Andrew Magarian .
- He was the Vice President of his High School, Joel E. Ferris, in Spokane, Washington.
- Once donated his hair to Locks of Love.
- Is 1/8 Cherokee.
- First cousin of Lindsey Trout .
- Avid and Licensed Skydiver with the United States Parachute Association.
- Ryan is childhood best friends with Ryan Lewis of the rap duo Macklemore & Ryan Lewis. Ryan and Ryan played in rock bands together throughout middle school and high school.
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