- His first name is actually pronounced in the traditional Irish way (Bree'un).
- He is from County Cavan in Ireland.
- In 2004 he withdrew from a Kennedy Center production of "A Streetcar Named Desire" starring Patricia Clarkson and girlfriend Amy Ryan in the role of Mitch in order to follow his hit off-Broadway show "Frozen" to Broadway. He subsequently won a Tony.
- Born in Ireland, O'Byrne has lived in New York for nearly 20 years and he is a devoted follower of the New York Mets.
- In 1998 he was nominated for a Tony Award for best actor for his role in Martin McDonagh's The Beauty Queen of Leenane.
- Appearing on Broadway in John Patrick Shanley's Doubt, a parable. This play won the 2005 Pulitzer Prize for Drama. (March 2005)
- Trained at the Samuel Beckett Center and Trinity College in Dublin.
- Won Broadway's 2004 Tony award as Best Actor (Featured Role - Play) for his performance as Ralph in "Frozen." This followed two Tony nominations for plays written by Martin McDonagh: in 1998 as Best Actor (Featured Role - Play) for "The Beauty Queen of Leenane;" and in 1999 as Best Actor (Play) for "The Lonesome West."
- Before he made his name on Broadway he used to perform in plays for a Theatre company he formed with writer Tony Kavanagh.
- Appearing on Broadway in Conor McPherson's "Shining City". (May 2006)
- In 1996 he became engaged to actress Amy Ryan.
- He was nominated for Outstanding Actor at the Drama Desk Awards for his role in Frozen.
- On Broadway, giving a Tony-nominated turn in the Tony-nominated trilogy "The Coast of Utopia". (June 2007)
- He won the 2004-2005 Drama Desk Award for Outstanding Actor for his Role in John Patrick Shanley's Doubt.
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