- O'Bannon and John Carpenter attended USC together; the result of their meeting each other in college was the low-budget cult science-fiction parody Dark Star (1974), which started out as a student movie and was eventually expanded into a theatrical feature.
- O'Bannon was reputed to suffer debilitating stress-induced stomach aches (which some detractors attributed to hypochondria). Upon his death, Diane O'Bannon revealed that her husband had been managing Crohn's Disease for about thirty years.
- Dan O'Bannon had been working on the screenplay for Screamers (1995) as early as 1981. The October 10, 1984, draft credits Michael Campus as co-writer. It is unknown whether Campus also intended to direct.
- He was considered one of the most brilliant, if volcanic, alumni of the USC film school.
- Has one son, Adam.
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