- Reprised Chop Top, his character in The Texas Chainsaw Massacre 2 (1986), in a film that was never released called "All American Massacre (2000)," which featured music from Buckethead.
- Has a band with Guns N' Roses guitar player Buckethead called "Cornbugs."
- Was friends with Timothy Leary.
- Got the part of Chop Top in The Texas Chainsaw Massacre 2 (1986) based on a cameo he did in a short film called The Texas Chainsaw Manicure.
- Has been in six movies with Tom Towles (Night of the Living Dead (1990), House of 1000 Corpses (2003), Home Sick (2007), The Devil's Rejects (2005) Grindhouse (2007), and Halloween (2007)).
- Was once a journalist, writing for such magazines as Omni, National Lampoon and Psychology Today.
- While many of his characters appear to be swamp people, Bill actually comes from an upper-class family with a strong connection to Yale University. He is the son of Virginia Gillette (Kleitz) and S. D. Moseley (Spencer Dumaresq Moseley). His mother was a journalist. His father was a captain and center of the 1942 Yale football team, a member of the Yale Corporation, and chairman and chief executive of the Railway Express Agency. Bill's paternal grandfather, George Moseley, was also a Yale football star. His maternal grandfather, William Lambert Kleitz, was a president and director of Guaranty Trust Co.
- Father, with Lucinda Jenney, of actress Marion Moseley.
- Was considered for the role of Captain James Deakins on Law & Order: Criminal Intent (2001).
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