20 wins & 34 nominations
- 2012 Nominee ALMA Award
- Favorite Movie Actress - Drama/Adventure
2006 Winner ALMA Award- Person of the Year
- 2021 Nominee Daytime Emmy
- Outstanding Directing Team for a Daytime Fiction Program
Shared with: Jody Margolin Hahn · Jeff Melman
- 2006 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 2012 Nominee People's Choice Award
- Favorite TV Drama Actress
- 2011 Nominee People's Choice Award
- Favorite TV Comedy Actress
- 2007 Winner People's Choice Award
- Favorite Female TV Star
- 2025 Winner Actor
- Outstanding Performance by an Ensemble in a Comedy Series
Shared with: Michael Cyril Creighton · Zach Galifianakis · Selena Gomez · Richard Kind · Eugene Levy · Steve Martin · Kumail Nanjiani · Molly Shannon · Martin Short - 2009 Nominee Actor
- Outstanding Performance by an Ensemble in a Comedy Series
Shared with: Kendall Applegate · Andrea Bowen · Charlie Carver · Max Carver · Ricardo Chavira · Marcia Cross · Dana Delany · James Denton · Lyndsy Fonseca · Rachel Fox · Teri Hatcher · Zane Huett · Felicity Huffman · Brent Kinsman · Shane Kinsman · Joy Jorgensen · Kyle MacLachlan · Neal McDonough · Joshua Logan Moore · Shawn Pyfrom · Doug Savant · Nicollette Sheridan · Brenda Strong - 2008 Nominee Actor
- Outstanding Performance by an Ensemble in a Comedy Series
Shared with: Andrea Bowen · Ricardo Chavira · Marcia Cross · Dana Delany · James Denton · Nathan Fillion · Lyndsy Fonseca · Rachel Fox · Teri Hatcher · Zane Huett · Felicity Huffman · Kathryn Joosten · Brent Kinsman · Shane Kinsman · Joy Jorgensen · Kyle MacLachlan · Shawn Pyfrom · Doug Savant · Dougray Scott · Nicollette Sheridan · John Slattery · Brenda Strong - 2007 Nominee Actor
- Outstanding Performance by an Ensemble in a Comedy Series
Shared with: Andrea Bowen · Richard Burgi · Mehcad Brooks · Ricardo Chavira · Marcia Cross · James Denton · Teri Hatcher · Josh Henderson · Zane Huett · Felicity Huffman · Kathryn Joosten · Nashawn Kearse · Brent Kinsman · Shane Kinsman · Joy Jorgensen · Kyle MacLachlan · Laurie Metcalf · Shawn Pyfrom · Doug Savant · Dougray Scott · Nicollette Sheridan · Brenda Strong · Kiersten Warren · Alfre Woodard - 2006 Winner Actor
- Outstanding Performance by an Ensemble in a Comedy Series
Shared with: Roger Bart · Andrea Bowen · Mehcad Brooks · Ricardo Chavira · Marcia Cross · Steven Culp · James Denton · Teri Hatcher · Felicity Huffman · Brent Kinsman · Shane Kinsman · Mark Moses · Doug Savant · Nicollette Sheridan · Brenda Strong · Alfre Woodard
- 2009 Nominee Teen Choice Award
- Choice Red Carpet Fashion Icon Female
- 2024 Winner Webby Award
- Podcasts - Scripted (Fiction) (Individual Episodes)
Shared with: Aaron Tracy · Rachel Winter - 2024 Winner People's Voice
- Podcasts - Scripted (Fiction) (Individual Episodes)
Shared with: Aaron Tracy
- 2014 Nominee BTVA Television Voice Acting Award
- Best Female Vocal Performance in a Television Series in a Guest Role - Comedy/Musical
As the voice of "Isabel Gutierrez". - 2014 Nominee BTVA Television Voice Acting Award
- Best Female Lead Vocal Performance in a Television Series - Comedy/Musical
As the voice of "Rudi Wilson".
- 2006 Nominee Gold Derby TV Award
- Ensemble of the Year
Shared with: Andrea Bowen · Mehcad Brooks · Richard Burgi · Ricardo Chavira · Marcia Cross · James Denton · Harriet Sansom Harris · Teri Hatcher · Zane Huett · Felicity Huffman · Cody Kasch · Brent Kinsman · Shane Kinsman · Joy Jorgensen · Mark Moses · Shawn Pyfrom · Doug Savant · Nicollette Sheridan · Brenda Strong · Alfre Woodard - 2005 Nominee Gold Derby TV Award
- Breakthrough Performer of the Year
- 2006 Nominee Bravo Otto Germany
- Best Female TV Star (TV-Star w)
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