- Doug's role in Guillermo del Toro's Pan's Labyrinth (2006) required him to learn huge amounts of dialog in archaic Spanish, which he did perfectly, but still was dubbed. Jones' learning the dialog so well made it easier for the dubbing actor to sync his voice to Jones' lip movement.
- Although his voice as 'Abe Sapien in Hellboy (2004) was dubbed by David Hyde Pierce, David refused a credit because he felt that Abe was entirely Doug's creation and did not wish to detract from his performance.
- The choker he often wears for promo appearances is one of Abe Sapien's eyes from Hellboy (2004).
- Was inspired to create Abe Sapien's graceful and liquid movements in Hellboy (2004) after watching the pet fish in his office.
- Frequently has a role in the films of Guillermo del Toro.
- Got his start in success when playing as Mac Tonight in the McDonald's Mac Tonight commercials.
- His makeup in Hellboy (2004) usually took six hours.
- His performance as Billy Butcherson in Hocus Pocus (1993) earned him a pre-nomination for a comedy award.
- Not only did Doug portray all four imps in the film Doom (2005), but he was also asked by director Andrzej Bartkowiak during filming to choreograph the movements of the Czech dancers who were hired to play zombies.
- He was the mascot for his college alma mater, Ball State University, where he performed as "Charlie the Cardinal" at many of the sporting and public events.
- Had a song called "The Devil and Mr. Jones" written about him by gothic rock singer-songwriter Aurelio Voltaire.
- Learned mime at Ball State University.
- Was the original actor to play the nefarious Tooth Fairy in Darkness Falls (2003) before Stan Winston came in and retooled the whole design.
- He got a half-inch chin implant, using some of the money he made from Batman Returns. (1992)
- Lives in California with his wife. (2004)
- Along with Sonequa Martin-Green and Emily Coutts, he is one of only three actors to appear in both the first and last episodes of Star Trek: Discovery (2017).
- Born on the same date as Kristin Scott Thomas.
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