Reese Witherspoon and Ashton Kutcher in Your Place or Mine (2023)

Reese Witherspoon and Patrick Dempsey in Sweet Home Alabama (2002)

Reese Witherspoon in Sweet Home Alabama (2002)

Jennifer Aniston and Reese Witherspoon in Testimony (2021)

Reese Witherspoon in A Private Person (2021)

Julianna Margulies and Reese Witherspoon in Laura (2021)

Jennifer Aniston, Reese Witherspoon, and Billy Crudup in It's Like the Flu (2021)

Reese Witherspoon and Hasan Minhaj in My Least Favorite Year (2021)

Jennifer Aniston, Reese Witherspoon, and Billy Crudup in The Morning Show (2019)

Jennifer Aniston and Reese Witherspoon in The Morning Show (2019)

Reese Witherspoon in Saturday Night Live (1975)

Reese Witherspoon in The Morning Show (2019)

Alan Rickman, Reese Witherspoon, Adam Sandler, Jack Black, and Lindsay Lohan in "The IMDb Show" On Location Goes Back to School (2019)

Jennifer Aniston, Reese Witherspoon, and Matthew Perry in Friends (1994)

Nicole Kidman, Laura Dern, Reese Witherspoon, Shailene Woodley, and Zoë Kravitz in The 69th Primetime Emmy Awards (2017)

Laura Dern, Reese Witherspoon, Shailene Woodley, and Zoë Kravitz in Big Little Lies (2017)

Reese Witherspoon, Will Ferrell, Margot, and Glen Wilson

Reese Witherspoon, Meredith Hagner, and Jimmy Tatro in You're Cordially Invited (2025)

Reese Witherspoon and Will Ferrell in You're Cordially Invited (2025)

Reese Witherspoon in Legally Blonde (2001)

Jennifer Aniston and Reese Witherspoon in The Overview Effect (2023)

Jennifer Aniston and Reese Witherspoon in Newscasters We Love From Film & TV (2023)

Reese Witherspoon, Colleen Camp, Matt Malloy, Loren Nelson, and Phil Reeves in Election (1999)

Reese Witherspoon and Mark Harelik in Election (1999)

Reese Witherspoon and Moonie in Legally Blonde (2001)

Reese Witherspoon in Legally Blonde 2: Red, White & Blonde (2003)

Ryan Phillippe, Reese Witherspoon, and Sarah Michelle Gellar in Cruel Intentions (1999)

Reese Witherspoon, Selma Blair, and Matthew Davis in Legally Blonde (2001)

Matthew Broderick and Reese Witherspoon in Election (1999)

Reese Witherspoon and Mark Ruffalo in Just Like Heaven (2005)