- Auditioned for the part of Gabriel Martin in The Patriot (2000), which eventually went to Heath Ledger, who died from an overdose of prescription drugs on January 22, 2008, exactly one week after Brad's death.
- Once roomed with Mark Foster, founding member of the band Foster the People.
- His favorite of his own movies was Bully (2001).
- A proficient guitar player who listed Led Zeppelin guitarist Jimmy Page as his idol.
- Raised by his grandmother, he was discovered by casting director Mali Finn, who was conducting a search for a kid to star in The Client (1994). Brad and his grandmother were flown to Hollywood for a screen test. Brad had never flown on a plane or stayed in a hotel before.
- Favorite actor was Steve McQueen.
- His grandmother, who had taken care of Brad from an early age, died February 1, 2008, of natural causes. She was 76 years old.
- He was originally cast as Will Rollins in Freddy vs. Jason (2003), but was replaced by Jason Ritter less than a week before filming began.
- He was discovered by casting director Mali Finn for the leading role in The Client (1994) when he was ten.
- Ex-girlfriend Anne Bergstedt established a memorial fund after Renfro's January 15, 2008, death from an overdose.
- Started playing guitar when he was 6 years old.
- Won the "Hollywood Reporter's Young Star Award" in 1995.
- Played in a school production sponsored by DARE, a program in which young people learn about the danger of drugs.
- Cousin of Jesse Hasek, singer for the band 10 Years from Knoxville, Tennessee.
- Half-sister: Haley Rose Olsen.
- Until he was discovered and cast in The Client (1994), he attended Fountain City Elementary School in Knoxville, Tennesee.
- His father, Mark, a factory worker, split from his wife while Brad was a toddler.
- The Official Brad Renfro Fan Club 322 Foxboro Dr. Walnut, CA 91789-2032 USA.
- Mother: Angela.
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