- Natasha was raised in a trailer park in Alberta, Canada. Her father was a biker/contractor and her mother was a housewife. She left her home at age 14 to move to Paris, France to become a model.
- Revealed in an interview with movie magazine "Empire" in 1998 that she is not very good at judging the scripts that are offered to her. She turned down both Independence Day (1996) and Men in Black (1997), thinking "What is this shit?" while reading the screenplays.
- Became legally emancipated from her parents at age 14 so that she could move to Paris, France to become a model.
- Gave birth to her second child at age 27, a son Asher Sky Waite in September 2001. Child's father is her now ex-boyfriend, Liam Waite.
- Gave birth to her first child at age 24, a son Tristan River Waite on October 12, 1998. Child's father is her now ex-boyfriend, Liam Waite.
- Ranked #1 of Sci-Fi's Sexy 50, by Femme Fatales magazine. (1997)
- Was asked to play the role of Jill Valentine in Resident Evil: Apocalypse (2004), but could not accept due to other work commitments.
- Filed for divorce from her second husband of two years Darius Campbell on July 23, 2014 following a 3-month-long separation.
- Was approached for the role of Dr. Christmas Jones in The World Is Not Enough (1999). However, she had just given birth to her first son right before casting started and couldn't accept the role. The role eventually went to Denise Richards.
- Ranked #85 in Stuff magazine's "102 Sexiest Women in the World". (2002)
- Dated Liam Waite from 1996 to 2004, and they have two sons together: Tristan River Waite (b. October 12, 1998) and Asher Sky Waite (b. September 2001).
- Celebrity judge at the Miss West Coast Pageant in Los Angeles, California on March 30, 2014.
- Not a relation with Elizabeth Henstridge, star of Agents of S.H.I.E.L.D. (2013).
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