Neil Patrick Harris, Alyson Hannigan, Jason Segel, Josh Radnor, and Cobie Smulders in How I Met Your Mother (2005)

Neil Patrick Harris, John Cho, and Kal Penn in A Very Harold & Kumar Christmas (2011)

Neil Patrick Harris, Nathan Fillion, Simon Helberg, and Felicia Day in Dr. Horrible's Sing-Along Blog (2008)

Neil Patrick Harris, Jason Robards, and Eva Marie Saint in My Antonia (1995)

Neil Patrick Harris, Matthew Lillard, and Amanda Peet in Animal Room (1995)

Neil Patrick Harris, David Burtka, Roy Haylock, Haneefah Wood, Latrice Royale, and Ryan A. Taylor in Drag Me to Dinner (2023)

Neil Patrick Harris, David Burtka, Roy Haylock, Haneefah Wood, and Murray Hill in Drag Me to Dinner (2023)

Jennifer Lopez and Neil Patrick Harris in How I Met Your Mother (2005)

Neil Patrick Harris and Barbara Nitke in Uncoupled (2022)

Neil Patrick Harris and Tisha Campbell in Uncoupled (2022)

Neil Patrick Harris in The Unbearable Weight of Massive Talent (2022)

Neil Patrick Harris in The Matrix Resurrections (2021)

Neil Patrick Harris in Doogie Howser, M.D. (1989)

Neil Patrick Harris, Patrice Goodman, Justin Sanchez, Amadi Chapata, Josh Cruddas, and Isaac Arellanes in Ghostwriter (2019)

Neil Patrick Harris and Shameik Moore in What to Watch with Your Family (2020)

Neil Patrick Harris in Visible: Out on Television (2020)

Neil Patrick Harris and Chris Sarandon in Stark Raving Mad (1999)

Neil Patrick Harris and Constance Wu in Constance Wu/Neil Patrick Harris/Sheryl Crow (2019)

Neil Patrick Harris in A Series of Unfortunate Events (2017)