Jennifer Aniston, Reese Witherspoon, and Billy Crudup in It's Like the Flu (2021)

Jennifer Aniston, Reese Witherspoon, and Billy Crudup in The Morning Show (2019)

Jennifer Aniston and Reese Witherspoon in The Morning Show (2019)

Jennifer Aniston and Scott Bakula in Quantum Leap (1989)

Jennifer Aniston and Jimmy Fallon in Saturday Night Live: The Best of Jimmy Fallon (2005)

Jennifer Aniston and Jon Lovitz in Friends (1994)

Jennifer Aniston in Jennifer Aniston (2020)

Jennifer Aniston in The Morning Show (2019)

Jennifer Aniston in Saturday Night Live (1975)

Jennifer Aniston, Reese Witherspoon, and Matthew Perry in Friends (1994)

Jennifer Aniston, Joanna Gleason, and Ralph Lauren in Friends (1994)

Jennifer Aniston, Matt LeBlanc, and David Schwimmer in Friends (1994)

Jennifer Aniston and Paul Rudd in The Object of My Affection (1998)

Jennifer Aniston and Reese Witherspoon in The Overview Effect (2023)

Jennifer Aniston and Reese Witherspoon in Newscasters We Love From Film & TV (2023)

Jennifer Aniston, Nigel Hawthorne, and Paul Rudd in The Object of My Affection (1998)

Jennifer Aniston, Adam Sandler, and Dany Boon in Murder Mystery (2019)

Jennifer Aniston and Adam Sandler in Murder Mystery 2 (2023)

Jennifer Aniston, Adam Sandler, and Luis Gerardo Méndez in Murder Mystery (2019)

Jennifer Aniston, Adam Sandler, and Luke Evans in Murder Mystery (2019)

Jennifer Aniston and Adam Sandler in Murder Mystery (2019)

Jennifer Aniston and Ben Affleck in He's Just Not That Into You (2009)

Jennifer Aniston and Reese Witherspoon in Testimony (2021)

Jennifer Aniston and Vince Vaughn in The Break-Up (2006)

Jennifer Aniston, Cameron Diaz, Sean Patrick Flanery, Sarah Michelle Gellar, and Edward Burns in She's the One (1996)

Jennifer Aniston, Cameron Diaz, Kevin Kline, Meg Ryan, and Edward Burns in French Kiss (1995)

Jennifer Aniston, Vincent Cassel, Clive Owen, RZA, and Xzibit in Derailed (2005)

Jennifer Aniston, Kevin Costner, John Cusack, Diane Lane, Jennifer Lopez, Jane Fonda, Shirley MacLaine, Mark Ruffalo, and Michael Vartan in Monster-in-Law (2005)

Jennifer Aniston, Joan Cusack, Frances McDormand, and Catherine Keener in Friends with Money (2006)