45 wins & 110 nominations
- 2024 Nominee Primetime Emmy
- Outstanding Drama Series
Shared with: Charlotte Stoudt · Kristin Hahn · Bill Kennedy · Lindsey Springer · Torrey Speer · Ronald Cosmo Vecchiarelli · Mallory Schwartz · Reese Witherspoon · John Blair · Lauren Levy Neustadter · Brian Stelter · Michael Ellenberg · Zander Lehmann · Emily Ferenbach · Joshua Allen · David Auge · Mimi Leder - 2021 Nominee Primetime Emmy
- Outstanding Variety Special (Pre-Recorded)
Shared with: Ben Winston · Kevin Bright · Marta Kauffman · David Crane · Courteney Cox · Lisa Kudrow · Matt LeBlanc · Matthew Perry · David Schwimmer · Emma Conway · James Longman · Stacey Thomas · Brett Blakeney · Dave Piendak · Carly Segal · Guy Harding · Paul Monaghan · James Corden · Tracie Fiss · Mike Darnell · Brooke Karzen - 2009 Nominee Primetime Emmy
- Outstanding Guest Actress in a Comedy Series
For playing "Claire". For episode "The One With The Cast Of 'Night Court'".
2016 Winner Special Award- Lifetime Achievement Award
- 2022 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Drama
- 2020 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Drama
- 2003 Winner Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 2002 Nominee Golden Globe
- Best Performance by an Actress in a Supporting Role in a Series, Miniseries or Motion Picture Made for Television
- 2000 Nominee Golden Satellite Award
- Best Performance by an Actress in a Series, Comedy or Musical
- 2019 Winner Special Achievement Award
- People's Icon
- 2024 Nominee PGA Award
- Outstanding Producer of Episodic Television, Drama
Shared with: Charlotte Stoudt · Mimi Leder · Michael Ellenberg · Reese Witherspoon · Lauren Levy Neustadter · Kristin Hahn · Zander Lehmann · Joshua Allen · Torrey Speer · Lindsey Springer · Bill Kennedy · Emily Ferenbach · Mallory Schwartz · Michelle Denise Jackson · Brian Stelter · John Blair · Ronald Cosmo Vecchiarelli
- 2012 Nominee Razzie Award
- Worst Screen Couple
Adam Sandler & EITHER Brooklyn Decker OR Jennifer AnistonShared with: Adam Sandler · Brooklyn Decker
- 2024 Nominee Actor
- Outstanding Performance by an Ensemble in a Drama Series
Shared with: Reese Witherspoon · Karen Pittman · Tig Notaro · Julianna Margulies · Greta Lee · Hannah Leder · Theo Iyer · Jon Hamm · Mark Duplass · Billy Crudup · Nestor Carbonell · Shari Belafonte · Nicole Beharie - 2022 Nominee Actor
- Outstanding Performance by an Ensemble in a Drama Series
Shared with: Shari Belafonte · Eli Bildner · Nestor Carbonell · Steve Carell · Billy Crudup · Mark Duplass · Amber Friendly · Janina Gavankar · Valeria Golino · Tara Karsian · Hannah Leder · Greta Lee · Julianna Margulies · Joe Marinelli · Michelle Meredith · Ruairi O'Connor · Joe Pacheco · Karen Pittman · Victoria Tate · Desean Terry · Reese Witherspoon
- 2005 Winner ShoWest Award
- Female Star of the Year
- 2000 Winner TV Guide Award
- Editor's Choice
Shared with: Courteney Cox · Lisa Kudrow · Matt LeBlanc · Matthew Perry · David Schwimmer · Jane Sibbett · John Christopher Allen
- 2004 Winner TV Prize
- Best Foreign TV Personality - Female (Bästa utländska kvinnliga tv-personlighet)
- 2003 Winner TV Prize
- Best Foreign TV Personality - Female (Bästa utländska kvinnliga tv-personlighet)
- 2002 Winner TV Prize
- Best Foreign TV Personality - Female (Bästa utländska kvinnliga tv-personlighet)
- 2001 Winner TV Prize
- Best Foreign TV Personality - Female (Bästa utländska kvinnliga tv-personlighet)
- 2007 Nominee TV Land Award
- Little Screen/Big Screen Star (Women)
- 2006 Nominee TV Land Award
- Little Screen/Big Screen Star (Women)
- 2005 Nominee TV Land Award
- Little Screen/Big Screen Star
- 2017 Winner EDA Special Mention Award
- Actress Most in Need of a New Agent
- 2012 Nominee EDA Special Mention Award
- Actress Most in Need of a New Agent
- 2011 Winner EDA Special Mention Award
- Actress Most in Need of a New Agent
- 2020 Nominee Shorty Award
- Best Celebrity
- 2023 Winner OFTA TV Hall of Fame
- Actors and Actresses
- 2024 Nominee Audience Choice Award
- Favourite Actress
- 2014 Nominee Georges Award
- Best Foreign Actress of the Decade
- 2014 Nominee Georges Award
- Best Foreign Actress of the Year
- 2012 Nominee Georges Award
- Best Foreign Actress of the Year
- 2024 Nominee Tell-Tale TV Award
- Favorite Performer in a Cable or Streaming Drama Series
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