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Mysterious deaths surround an American ambassador. Could the child that he is raising actually be the Antichrist? The Devil's own son?

Damien the Antichrist, now about to turn thirteen years old, finally learns of his destiny under the guidance of an unholy disciple of Satan. Meanwhile dark forces begin to eliminate all those who suspect the child's true identity.

The now adult Antichrist plots to eliminate his future divine opponent while a cabal of monks plot to stop him.

Two attorneys adopt a mysterious orphan girl as their daughter, unaware she is the new Antichrist, next in line to Damien Thorn.