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Two FBI agents - one guided by reason, and another by intuition - looking for missing people in Washington, D.C.

Brooke attempts to stop the execution of what she believes to be an innocent man.

A family is attacked. The father is killed, the mother is beaten, and their twin daughters disappear.

The loss of a team member results in the team facing a psychiatric evaluation. The team looks for a legal secretary.

Jess has a vision that leads her and Nicole to discover a 10-year-old skeleton. When the body is identified, Pollack orders them off the case. Jess and Nicole continue to work on the case while trying to keep their work away from Pollack and trying to figure out why he's so insistent that they can't work on it. Meanwhile, Pollack's wife Janice kicks him out.

Part one of two. The team hunts for a heavily pregnant woman who has been snatched from the streets. After talking to the victim's doctor, they begin to suspect another patient may be involved.

A newborn is kidnapped.

Against Brooke's wishes, Jess goes under cover at a military academy.

A cop is found shot and his partner is missing. Jess is tasked with finding the missing officer.

The team travel to Budapest in search of a man who goes missing after having plastic surgery.

Nicole goes under a dangerous arms-dealer.

Jess and Brooke investigate the disappearance of a wealthy couple in the wilds of northern Michigan.

Jess becomes delusional while trying to track a serial killer.

A seemingly 'normal' suburban family goes missing. Nicole seems enamoured with the "white picket fences".

A press reports compromises a DoJ agent who is then abducted from the street.

A molecular biologist goes missing, reuniting Brooke with her father. Jess meets Jack Burgess.

Dylan Anders, a convict about to go on trial for murder, kills two police officers and escapes. He then steals a Dr. Laurel Bennett's car and kidnaps her. Jess, Nicole, Antonio and Janey are assigned to the case and Jess and Nicole eventually rescue Dr. Bennett from a burning building. Meanwhile, Nicole urges Jess to get to know Janey better and the three women urge Antonio to keep his job instead of taking a new job in airline security. Back on the case, the mystery only begins and it is eventually learned that Dr. Tanner is helping Anders instead putting the FBI off his trail. It culminates at a drugstore where one of the FBI's own is fatally wounded in a shootout with Anders.

Nicole is in a car accident, with Jess having power of attorney. While a wealthy man's son goes missing.

Jess investigates when a teenage girl's parents vanish from a gas station, leaving their car and everything behind.

A woman is found murdered in Central Park, but the body disappears before the killer can be found - while Jess's dreams revolve around the victim in an electric chair.

Jess experiences troubling nightmares as she tries to locate a missing woman who has been threatened by a killer.

After arresting a dangerous man on the run, Jess and Nicole find a man shot in the head hanging on to life in the trunk of the car he was trying to steal. The man has amnesia and doesn't remember anything. The bullet leads the team to believe that he's connected in some way to the disappearance of young heiress Victoria Farlow and they must decide if "John Doe" is innocent or guilty while trying to figure out his identity and the circumstances of his near-death.

A judge has her daughter kidnapped.

The team hunt for a boy after he disappears while in his grandmother's care.

A bus is hijacked and 20 people are kidnapped by men looking for their partner in a bank robbery. One of the people kidnapped is an 8 month pregnant woman who's baby's heartbeat features prominently in Jess's visions.