El Chapo asks Chito for help so that he can escape from prison in exchange for making him part of his team. Conrado is looking for Mirta to offer his services against narco and thus be able to put himself back into the government.
Joaquín Guzmán Loera sets a trap for Raciel Cárdenas to be captured and take over the territory of Nuevo Laredo. 'El Chapo' and 'La Federación' begin a war against 'El Cano' and the bloodthirsty army of 'Los Emes'.
Joaquín Guzmán Loera promises 'Don Sol' to end the failed war against drug trafficking and pacify the country. Thousands of innocent people suffer the terrible consequences of the clashes between 'The Federation', 'The Emes' and 'Chente'.
Joaquín Guzmán Loera orders the hunt of Arturo Bernal Leyda, who attacks him in his territory of Sinaloa with the help of 'El Cano' and 'Chente'. Nazario Moreno walks out of 'La Federación' after 'El Chapo's new war.
Pain gets hold of Joaquín Guzmán Loera after the murder of his son, 'El Moreno', so he leaves Ismael in charge of the war. 'Don Sol' fears that 'El Cano', 'Chente' and Arturo Bernal Leyda might use 'El Chapo's weakness in their favor.