The Big Bang Theory (2007– )
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The Brain Bowl Incubation 

A proposition by Sheldon shocks Amy. Raj takes an interest in someone at the university.


Mark Cendrowski


Chuck Lorre (created by), Bill Prady (created by) | 6 more credits »

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Episode complete credited cast:
Johnny Galecki ... Leonard Hofstadter
Jim Parsons ... Sheldon Cooper
Kaley Cuoco ... Penny Hofstadter
Simon Helberg ... Howard Wolowitz
Kunal Nayyar ... Raj Koothrappali
Mayim Bialik ... Amy Farrah Fowler
Melissa Rauch ... Bernadette Rostenkowski
Maria Canals-Barrera ... Issabella


Despite the parts that he doesn't like about it, Amy is able to convince Sheldon to take a skin sample from him so that she can develop a brain cell from a combination of both his and hers. Sheldon is so enamored with the result of Amy's experiment that he proposes something else that shocks Amy. Sheldon does whatever he can to convince Amy to go along - those measures which would normally excite her - but she resists to the best of her ability if only because of what the end result would be. Meanwhile, Raj has met a woman, Issabella, at the university to who he is attracted, and who he would like to start dating. Beyond that physical and emotional attraction he has to her, there is one aspect of her being about which he may not be able to overcome and which colors what he says about her to his friends. Written by Huggo

Plot Summary | Add Synopsis


Comedy | Romance


TV-PG | See all certifications »





English | Spanish

Release Date:

10 November 2016 (USA) See more »

Company Credits

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Technical Specs


Sound Mix:




Aspect Ratio:

16:9 HD
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Did You Know?


Title Reference: Sheldon and Amy mix their DNA and incubate some brain cells. See more »


[first lines]
Sheldon Cooper: How much will it hurt?
Amy Farrah Fowler: It's just a tiny skin sample. You saw my do it to myself.
Sheldon Cooper: On a scale of one to ten, where one is a pebble in your shoe and ten is the monkey you thought was your pet biting your face off.
Amy Farrah Fowler: A two.
Sheldon Cooper: Eating a whole Altoid?
Amy Farrah Fowler: Sheldon, if I'm going to synthesize a neural network from our skin cells, I need to harvest them. Now, I've done this dozens of times, but if you're too scared you don't have to.
Sheldon Cooper: No, this is for science. I can be brave for science.
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Crazy Credits


Uh-oh. See more »


History of Everything
Written by Barenaked Ladies
Performed by Barenaked Ladies
[Series theme song played during the opening titles]
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User Reviews

Picking up for the First Time in Years!
12 November 2016 | by Robinson2511See all my reviews

Ever since the show's 7th season, The Big Bang Theory has been spewing out endless stories that have either been underwhelming, uninteresting, or just really unfunny.

There hasn't been an episode since the 6th series that I've really wanted to remember, not The Opening Night Excitation, not The Meemaw Materialisation, not even The Scavenger Vortex, because, although they're good enough in their own right, they're far from the show's glory days.

I've sat patiently through the last 3 years of the show, and instead of watching plot developments and characters progress, I've watched the humour leak out of the show until there's not a lot left but irritating melodrama. Until now...

The Brain Bowl Incubation is the first time in years that this show has seriously made me laugh. It got everything right, it's spontaneous, it's outrageous, it gets the characters just right, and finally, Sheldon has a purpose again other than to be the hideously drawn-out gag machine.

We finally get some character from Raj who drifted through series 9 on autopilot, and Bernadette was put on the backseat so other characters could come to the forefront.

If the series continues at this pace, it could return to its golden age, and be a show that exists because it funny again, not just because it's making Chuck Lorre a tonne of money.

The Big Bang Theory has some great plots coming, but the humour has been lacking. This episode serves to remind us what this show can be when it puts the effort in.

It reminds me of Lorre's writing from the Sheen years of Two and a Half Men. Outrageous and superbly witty. If he can recapture that, then this show has a long future ahead of it.

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